Volume 154, Issue 3, Pages (September 2018)

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Volume 154, Issue 3, Pages 722-725 (September 2018) Multiplex PCR on the Bronchoalveolar Lavage Fluid of Immunocompromised Patients Kristina Affolter, MD, Desiree M. Schumann, PhD, Michael Tamm, MD, Kathleen Jahn, MD, Aline Siebeneichler, MD, Lilian Junker, MD, Karoline Wagner, PhD, Peter M. Keller, MD, Reno Frei, MD, Daiana Stolz, MD, MPH, FCCP CHEST Volume 154, Issue 3, Pages 722-725 (September 2018) DOI: 10.1016/j.chest.2018.06.018 Copyright © 2018 American College of Chest Physicians Terms and Conditions

Figure 1 Diagnostic performance of the Unyvero P55 Assay on BAL from 522 cases of immunocompromised patients using conventional methods as the gold standard and stratifying for antibiotics, Gram staining, and infiltrates. NLR = negative likelihood ratio; NPV = negative predictive value; PLR = positive likelihood ratio; PPV = positive predictive value. CHEST 2018 154, 722-725DOI: (10.1016/j.chest.2018.06.018) Copyright © 2018 American College of Chest Physicians Terms and Conditions

Figure 2 Comparing the percentage of cases positive for bacteria by using multiplex assay and conventional methods (A) 24 h, (B) 3 days, and (C) 7 days following hospital admission to bronchoscopy. The percent bacteria identified were stratified according to antibiotic pretreatment and presence of infiltrates. PCR = polymerase chain reaction. CHEST 2018 154, 722-725DOI: (10.1016/j.chest.2018.06.018) Copyright © 2018 American College of Chest Physicians Terms and Conditions