Jason M. Gauthier, MD, Andrew J

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Presentation transcript:

Chest computed tomography imaging improves potential lung donor assessment  Jason M. Gauthier, MD, Andrew J. Bierhals, MD, MPH, Jingxia Liu, MS, PhD, Keki R. Balsara, MD, Christine Frederiksen, MS, Emily Gremminger, BA, Ramsey R. Hachem, MD, Chad A. Witt, MD, Elbert P. Trulock, MD, Derek E. Byers, MD, PhD, Roger D. Yusen, MD, MPH, Patrick R. Aguilar, MD, Gary Marklin, MD, Ruben G. Nava, MD, Benjamin D. Kozower, MD, MPH, Michael K. Pasque, MD, Bryan F. Meyers, MD, MPH, G. Alexander Patterson, MD, Daniel Kreisel, MD, PhD, Varun Puri, MD, MSCI  The Journal of Thoracic and Cardiovascular Surgery  Volume 157, Issue 4, Pages 1711-1718.e1 (April 2019) DOI: 10.1016/j.jtcvs.2018.11.038 Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Potential lung donor with findings of emphysema on chest computed tomography imaging. The images shown are from a potential donor 64 years of age who died from a cerebrovascular accident. The potential donor achieved a best partial pressure of oxygen of 572 mm Hg (optimal) and had a positive smoking history. (A) Chests x-ray image from the potential lung donor is normal. (B) Chest computed tomography scan reveals bilateral lung destruction and hyperexpansion typical of emphysema. The donor lungs were declined for transplantation. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 1711-1718.e1DOI: (10.1016/j.jtcvs.2018.11.038) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Potential lung donor with findings of interstitial lung disease on chest computed tomography imaging. The images shown are from a potential donor 33 years of age who died from drug intoxication. The potential donor achieved a best partial pressure of oxygen of 313 mm Hg (optimal) and had a negative smoking history. (A) Chest x-ray from the potential lung donor reveals mild bilateral patchy opacities without consolidation. (B) Chest computed tomography scan reveals subpleural reticulation and ground glass (arrows) consistent with interstitial lung disease (nonspecific interstitial pneumonia). The donor lungs were declined for transplantation. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 1711-1718.e1DOI: (10.1016/j.jtcvs.2018.11.038) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Potential lung donor with findings of traumatic lung injury on chest computed tomography imaging. The images shown are from a potential donor 23 years of age who died from head trauma. The potential donor achieved a best partial pressure of oxygen of 500 mm Hg (optimal) and had a negative smoking history. (A) Chest x-ray from the potential lung donor reveals bilateral central opacities. (B) Chest computed tomography scan reveals findings consistent with pulmonary contusions and traumatic lung injury. The donor lungs were used for transplantation. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 1711-1718.e1DOI: (10.1016/j.jtcvs.2018.11.038) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

CT findings of structural lung disease are negatively associated with lung utilization. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 1711-1718.e1DOI: (10.1016/j.jtcvs.2018.11.038) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Video 1 The lead author discusses the present study's background, results, and implications for lung donor assessment. Video available at: https://www.jtcvs.org/article/S0022-5223(18)33147-7/fulltext. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 1711-1718.e1DOI: (10.1016/j.jtcvs.2018.11.038) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions