Phase II Trial of Graft-versus-Host Disease Prophylaxis with Post-Transplantation Cyclophosphamide after Reduced-Intensity Busulfan/Fludarabine Conditioning.

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Presentation transcript:

Phase II Trial of Graft-versus-Host Disease Prophylaxis with Post-Transplantation Cyclophosphamide after Reduced-Intensity Busulfan/Fludarabine Conditioning for Hematological Malignancies Amin M. Alousi, Jonathan E. Brammer, Rima M. Saliba, Borje Andersson, Uday Popat, Chitra Hosing, Roy Jones, Elizabeth J. Shpall, Issa Khouri, Muzaffar Qazilbash, Yago Nieto, Nina Shah, Sairah Ahmed, Betul Oran, Gheath Al Atrash, Stefan Ciurea, Partow Kebriaei, Julianne Chen, Gabriela Rondon, Richard E. Champlin Biology of Blood and Marrow Transplantation Volume 21, Issue 5, Pages 906-912 (May 2015) DOI: 10.1016/j.bbmt.2015.01.026 Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Comparison of Acute GVHD II to IV (A), acute GVHD III/IV (B), nonrelapse mortality (C), relapse (D) and overall survival (E) in recipients of GVHD prophylaxis with Post-CY (dashed line) and tacrolimus/methotrexate (solid line) after RIC allogeneic transplantations from MRD and MUDs. Biology of Blood and Marrow Transplantation 2015 21, 906-912DOI: (10.1016/j.bbmt.2015.01.026) Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions