Bone-seeking superparamagnetic iron oxide nanoparticles (SPIONs) for magnetic resonance imaging of bone turnover in early osteoarthritis  A. Panahifar,

Slides:



Advertisements
Similar presentations
Validity and responsiveness of a new measure of knee osteophytes for osteoarthritis studies: data from the osteoarthritis initiative  M. Hakky, M. Jarraya,
Advertisements

An Investigation of High Density Mineralised Protrusions in Human Cadaveric Knees by MRI and Microtomography  N.P. Thomas, N. Jeffery, R. van 't Hof,
Osteoarthritis and Cartilage
7th International Workshop on Osteoarthritis Imaging report: “imaging in OA – now is the time to move ahead”  A. Guermazi, F. Eckstein, D. Hunter, F.
Early Effects of HIP Arthroscopy on Articular Cartilage Composition in Femoroacetabular Impingement Patients  M.A. Samaan, A.L. Zhang, M.C. Gallo, T.M.
S. Gavard  Osteoarthritis and Cartilage 
Development and reliability of a multi-modality scoring system for evaluation of disease progression in pre-clinical models of osteoarthritis: celecoxib.
Bone marrow lesions on magnetic resonance imaging in hand osteoarthritis are associated with pain and interact with synovitis  R. Liu, W. Damman, M. Reijnierse,
Positron emission tomography with 18F-FDG in osteoarthritic knee
Advances in visualization of knee cartilage and meniscal morphology with standing computed tomography  N.A. Segal, A. Guermazi  Osteoarthritis and Cartilage 
Sensitivity to Change of 3D Meniscal Measures in Rapidly Progressing Knee Osteoarthritis and Association With Radiographic Joint Space Width Loss  M.
Biochemical markers of synovial inflammation – Surrogate markers of synovitis on magnetic resonance imaging? – Data from the osteoarthritis initiative 
Quantitatively-measured bone marrow lesions in the patellofemoral joint: distribution and association with pain  C. Ratzlaff, R. Russell, J. Duryea  Osteoarthritis.
Accuracy and test–retest precision of quantitative cartilage morphology on a 1.0T peripheral magnetic resonance imaging system  D. Inglis, Ph.D., M. Pui,
Role of endothelin-1 in endochondral ossification and osteoarthritis
Association between tibial subchondral bone structure from plain radiographs and cartilage composition from quantitative MRI in postmenopausal women with.
Automatic cartilage segmentation and measurement for diagnosis of OA using 3D box and Gaussian filters  X. Cui, S. Li, M. Yu, H. Kim, K.-S. Kwack, B.-H.
Volumetric and semiquantitative assessment of MRI-detected subchondral bone marrow lesions in knee osteoarthritis: a comparison of contrast-enhanced and.
Effect of self assembled peptide-mesenchymal stem cell complex on delaying the progression of osteoarthritis  S. Kim, S. Lee, Y. Jung, J. Kim, S. Kim 
Quantitative T1ρ, T2 and T2* mapping of articular cartilage changes in a rat model of osteoarthritis using in vivo high-resolution magnetic resonance.
S. Reichenbach, M. D. , A. Guermazi, M. D. , J. Niu, M. B. B. S. , D
Comparison of the Usefulness of Laser-induced Photoacoustic Measurement & Magnetic Resonance Imaging (T2 Mapping, Diffusion Tensor Imaging) for Assessing.
The differences on extracellular matrix among each portion of meniscus
Potential mechanism of alendronate inhibition of osteophyte formation in the rat model of post-traumatic osteoarthritis: evaluation of elemental strontium.
Between-group differences in infra-patellar fat pad size and signal in symptomatic and radiographic progression of knee osteoarthritis vs non-progressive.
Associations between magnetic resonance imaging-defined structural pathologies and generalized and localized knee pain – the Oulu Knee Osteoarthritis.
Investigating the role of bone microarchitecture in early osteoarthritis using new in vivo 3D high-resolution peripheral quantitative computed tomography 
T. Nozaki, Y. Kaneko, H. Yu, K. Kaneshiro, R. Schwarzkopf, T. Hara, H
Knee pain and inflammation in the infrapatellar fat pad estimated by conventional and dynamic contrast-enhanced magnetic resonance imaging in obese patients.
B. Vafaeian, S. Adeeb, M. El-Rich, J. Jaremko 
Two different knee braces alter patella position: a moving image analysis using weight bearing magnetic resonance imaging  M.J. Callaghan, N.D. Reeves,
Mice with global deletion of mitogen inducible gene 6 display rapid and severe cartilage and subchondral bone damage after ligament and meniscus injury 
M. Wang, A. Radjenovic, T. W. Stapleton, R. Venkatesh, S. Williams, E
D. Hayashi, F.W. Roemer, A. Guermazi  Osteoarthritis and Cartilage 
S. Hagiwara, A. Yang, M. Soltanolkotabi, S. Takao, Y. Kaneko, T
Bone marrow lesions and joint effusion are strongly and independently associated with weight-bearing pain in knee osteoarthritis: data from the osteoarthritis.
J. A. Gallagher, N. Thomas, J. L. Donnelly, N. Jeffery, D. Mills, G. R
Structural changes in the knee during weight loss maintenance after a significant weight loss in obese patients with osteoarthritis: a report of secondary.
Comments on Beattie et al
F.W. Roemer, M.D.  Osteoarthritis and Cartilage 
Who should have a joint replacement? A plea for more ‘phronesis’
Relevance of imaging in anti nerve growth factor inhibitor (aNGF) studies with a focus on eligibility and on-study safety – A pictorial overview  F.W.
Magnetic resonance imaging (MRI)-defined cartilage degeneration and joint pain are associated with poor physical function in knee osteoarthritis – the.
Subchondral Bone Plate Sclerosis during Late Osteoarthritis is Mediated by Loading- induced Decrease in Sclerostin Amount  X. Ma, H. Jia, W. Tong, Z. Yang,
Effects of low level laser therapy: a study of status of cartilage, subchondral bone and gait adaptation in the rat anterior cruciate ligament transection.
Structural Damage of the Thumb Base in Patients With Hand Osteoarthritis, Assessment by Magnetic Resonance Imaging Compared to Standard Radiography  S.
Three dimensional distribution of hip cartilage t2 mapping assessed by radial mr imaging: comparison between healthy volunteers and patients with hip.
Medial meniscus posterior horn zones show differing responses to static loading in subjects with knee osteoarthritis compared to controls  N.E. Calixto,
Magnetic resonance imaging in osteoarthritis: which method best reflects synovial membrane inflammation?  D. Loeuille, A.-C. Rat, J.-C. Goebel, J. Champigneulle,
A novel method for assessing signal intensity within infrapatellar fat pad on MR images in patients with knee osteoarthritis  M. Lu, Z. Chen, W. Han,
Z. Huang, T. Stabler, F. Pei, V. Kraus  Osteoarthritis and Cartilage 
Finite element analysis of mechanical behavior of human dysplastic hip joints: a systematic review  B. Vafaeian, D. Zonoobi, M. Mabee, A.R. Hareendranathan,
A pilot study of the reproducibility and validity of measuring knee subchondral bone density in the tibia  D. Dore, BBiotech.(Hons.), C. Ding, M.D., G.
D.J. Hunter  Osteoarthritis and Cartilage 
Evidence for bone mineral density and bone resorption in middle and elderly women with knee osteoarthritis in Shanghai: a cross sectional study  Q. Xiaofeng 
Multivariate pattern analysis of physical activity and cartilage health: data from the osteoarthritis initiative  E. Halilaj, T.J. Hastie, G.E. Gold,
3D modelling of the hip joint from clinical imaging data
Location-specific hip joint space width for progression of hip osteoarthritis: predictive validity and responsiveness of a new computerized measure  C.
Imaging biomarker with T1 and T2 mappings in osteoarthritis – In vivo human articular cartilage study  C. Yan, C. Wong, T. Li, N. Gong, Q. Chan, K. Chiu 
Nanoparticle targeting to cartilage: effects of surface charge on nanoparticle interactions with joint tissues  S.B. Brown, B. Sharma  Osteoarthritis.
Statistical simulation using data from the foundation for the national institute of health/osteoarthritis initiative biomarkers consortium to evaluate.
Osteoarthritis and Cartilage
Knee cartilage defects: association with early radiographic osteoarthritis, decreased cartilage volume, increased joint surface area and type II collagen.
Knee kinematic and kinetic modifications under body weight unloading during overground walking at a constant speed  A.G. Fischer, E.M. Debbi, A. Wolf 
E. M. Debbi, B. Bernfeld, E. Gray, M. Salai, Y. Levy, A. Gold, R
E. M. Debbi, B. Bernfeld, M. Falah, A. Greental, A. Sigal, R. Debi, A
Osteoarthritis and Cartilage
Quantifying biochemical changes in the cartilage matrix in osteoarthritic knee after hyaluronic acid injection using quantitative MR techniques  A.R.
General Information Osteoarthritis and Cartilage
Long-term effects of vitamin d supplementation and maintaining vitamin d sufficiency on knee osteoarthritis over 5 years  B. Antony, S. Zheng, J. Burgess,
Presentation transcript:

Bone-seeking superparamagnetic iron oxide nanoparticles (SPIONs) for magnetic resonance imaging of bone turnover in early osteoarthritis  A. Panahifar, J.L. Jaremko, M. Mahmoudi, R.G. Lambert, W.P. Maksymowych, M.R. Doschak  Osteoarthritis and Cartilage  Volume 22, Pages S256-S257 (April 2014) DOI: 10.1016/j.joca.2014.02.488 Copyright © 2014 Terms and Conditions

Fig. Intermediate T2-weighted fat-suppressed MRI: Sagittal plane showing ‘negative enhancement’ of the joint (medial) at femoral trochlear and condylar subchondral bone (arrows) as well as the growth plate (red box), with dark bands developing after SPIONs-ALN injection. Osteoarthritis and Cartilage 2014 22, S256-S257DOI: (10.1016/j.joca.2014.02.488) Copyright © 2014 Terms and Conditions