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Volume 8, Issue 3, Pages 197-203 (June 2002) Derangement of autonomic nerve control in rat with right ventricular failure S.N. Sanyal, K. Ono Pathophysiology Volume 8, Issue 3, Pages 197-203 (June 2002) DOI: 10.1016/S0928-4680(02)00002-0

Fig. 1 Electrocardiogram (ECG), trendgram of RR intervals and power spectrograms in a control Wistar rat and in an MCT-treated rat. A representative ECG record for 1.6 s in a control rat (A) and in an MCT-treated rat (B). Trendgrams of RR intervals for 300 s obtained from a control rat (C) and an MCT-treated rat (D). Short thick bars in panels C and D indicate time during ECG records (panels A and B) were obtained. Power spectra of heart rate (RR interval) fluctuations (E, F) deduced from the trendgrams in (C) and (D), respectively. Pathophysiology 2002 8, 197-203DOI: (10.1016/S0928-4680(02)00002-0)

Fig. 2 Group data of heart rate (HR) and spectral parameters in control Wistar rats and in MCT-treated rats. (A) HR; (B) Total power (TP); (C) HF power and (D) the ratio of LF to HF power (L/H): the number of experimental animals is given in parentheses. *P<0.05, ***P<0.001. Pathophysiology 2002 8, 197-203DOI: (10.1016/S0928-4680(02)00002-0)

Fig. 3 Effects of atropine on HR and power spectral parameters in control Wistar rats and in MCT-treated rats. HR (A, B) and the other parameters, TP (C, D), HF (E, F) and L/H ratio (G, H), in the control rats and in the MCT-treated rats were obtained from ECG records prior to and 30 min after the injection of atropine (2 mg/kg). The number of experimental animals is given in parentheses. *P<0.05, **P<0.01, ***P<0.001. Pathophysiology 2002 8, 197-203DOI: (10.1016/S0928-4680(02)00002-0)

Fig. 4 Effects of propranolol on HR and power spectral parameters in control Wistar rats and in MCT-treated rats. HR (A, B) and the other parameters, TP (C, D), HF (E, F) and L/H ratio (G, H), in the control rats and in the MCT-treated rats were obtained from ECG records prior to and 30 min after the injection of propranolol (4 mg/kg). The number of experimental animals is given in parentheses. *P<0.05, **P<0.01, ***P<0.001. Pathophysiology 2002 8, 197-203DOI: (10.1016/S0928-4680(02)00002-0)