Natural selection of K13 mutants of Plasmodium falciparum in response to artemisinin combination therapies in Thailand C. Putaporntip, N. Kuamsab, R.

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Presentation transcript:

Natural selection of K13 mutants of Plasmodium falciparum in response to artemisinin combination therapies in Thailand C. Putaporntip, N. Kuamsab, R. Kosuwin, W. Tantiwattanasub, P. Vejakama, T. Sueblinvong, S. Seethamchai, S. Jongwutiwes, A.L. Hughes Clinical Microbiology and Infection Volume 22, Issue 3, Pages 285.e1-285.e8 (March 2016) DOI: 10.1016/j.cmi.2015.10.027 Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

Fig. 1 Map of Thailand illustrating provinces from which samples were collected. Clinical Microbiology and Infection 2016 22, 285.e1-285.e8DOI: (10.1016/j.cmi.2015.10.027) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

Fig. 2 Plot of frequency of mutant haplotypes in propeller region vs. year of sample collection for samples with nonsynonymous diversity in propeller region (r = 0.780; p = 0.013). Clinical Microbiology and Infection 2016 22, 285.e1-285.e8DOI: (10.1016/j.cmi.2015.10.027) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions