Immunohistochemistry staining of interferon (IFN)-λ in renal tissue. Immunohistochemistry staining of interferon (IFN)-λ in renal tissue. The figure demonstrates a kidney biopsy from a patient with lupus nephritis class IV. The representative micrograph displays IFNλ staining predominantly found in tubular cells and in an incipient cellular crescent in the glomeruli. In the glomeruli without crescent, the staining is sparse. Original magnifications: ×20. Agneta Zickert et al. Lupus Sci Med 2016;3:e000170 ©2016 by Lupus Foundation of America