Effects of in vivo exercise on ankle cartilage deformation and recovery in healthy volunteers: an experimental study A. Van Ginckel, P. Roosen, K.F.

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Effects of in vivo exercise on ankle cartilage deformation and recovery in healthy volunteers: an experimental study A. Van Ginckel, P. Roosen, K.F. Almqvist, K. Verstraete, E. Witvrouw Osteoarthritis and Cartilage Volume 19, Issue 9, Pages 1123-1131 (September 2011) DOI: 10.1016/j.joca.2011.06.009 Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Sequence of events during the experimental procedures. Osteoarthritis and Cartilage 2011 19, 1123-1131DOI: (10.1016/j.joca.2011.06.009) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 sag3D DESS WE image of tibial and talar cartilage. Top: without masks; bottom left: with talar mask; bottom right: with tibial mask. Osteoarthritis and Cartilage 2011 19, 1123-1131DOI: (10.1016/j.joca.2011.06.009) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Illustration of the determination of relative surface area use for talar cartilage plates. Images are screenshots taken from the Mimics user interface. Red volumes are the post-exercise 3D volumes, dark blue volume is the pre-exercise volume, light blue volume is the primarily loaded surface of the pre-exercise volume. Wherever light blue shades are present, volumes have decreased after the exercise13. Similar procedures were applied on tibial cartilage. Osteoarthritis and Cartilage 2011 19, 1123-1131DOI: (10.1016/j.joca.2011.06.009) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Fig. 4 The course of deformation and recovery time for talar (a) and tibial (b) cartilage displayed using means of absolute 3D volumes (mm3) (S.D.) at the five time points under study. tpre: 3D volume before the exercise; tpostt0–15–30-45: 3D volume immediately, 15min, 30min, 45min after the exercise respectively. Osteoarthritis and Cartilage 2011 19, 1123-1131DOI: (10.1016/j.joca.2011.06.009) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions