Retinoic acid enhances lung growth after pneumonectomy

Slides:

Advertisements

Similar presentations

Aprotinin improves pulmonary function during reperfusion in an isolated lung model Menen A Mathias, MD, Curtis G Tribble, MD, Jeffrey F Dietz, BS, Richard.

Advertisements

Leo M. Gazoni, MD, Lynn M. Fedoruk, MD, John A. Kern, MD, John M

Bilateral Internal Mammary Artery Use for Coronary Artery Bypass Grafting Remains Underutilized: A Propensity-Matched Multi-Institution Analysis Damien.

The STS National Database

Neonatal Flail Tricuspid Valve: Diagnosis and Management

Methylene Blue for Vasoplegic Syndrome After Cardiac Operation: Early Administration Improves Survival J. Hunter Mehaffey, MD, Lily E. Johnston, MD,

Preoperative Laparoscopic Ligation of the Left Gastric Vessels in Preparation for Esophagectomy Ninh T. Nguyen, MD, Mario Longoria, MD, Allen Sabio,

Michael M. Mauney, MD, David C. Cassada, MD, Aditya K

Robert J Cerfolio, MD, Cyndi Bass, MSN, Charles R Katholi, PhD

Hospital Variation in Mortality From Cardiac Arrest After Cardiac Surgery: An Opportunity for Improvement? Damien J. LaPar, MD, MS, Ravi K. Ghanta, MD,

Meta-Analysis of Survival After Pleurectomy Decortication Versus Extrapleural Pneumonectomy in Mesothelioma Emanuela Taioli, MD, PhD, Andrea S. Wolf,

Burdens Without Blessings: Peer Reviewers Get No Respect

David T. Cooke, MD, Danh V. Nguyen, PhD, Ying Yang, MS, Steven L

Michelle C. Ellis, MD, Brian S. Diggs, PhD, John T. Vetto, MD, Paul H

Expression of Bone Morphogenetic Proteins in Human Lung Carcinomas

Philip W. Smith, MD, Hongkun Wang, PhD, Leo M. Gazoni, MD, K

Varun Puri, MD, Andrew Tran, MS, Jennifer M. Bell, BS, Traves D

Positron Emission Tomography-Computed Tomography for Postoperative Surveillance in Non-Small Cell Lung Cancer Se Hoon Choi, MD, Young Tae Kim, MD, PhD,

Pleural Metastasis of Osteosarcoma

Public policy and the practicing physician

Asad A. Shah, MD, Mathias Worni, MD, MHS, Christopher R

Origins of the Cardiothoracic Surgery Network (CTSNet)

Abbas Emaminia, MD, Damien J

Who Do You Say You Are? The Annals of Thoracic Surgery

Damien J. LaPar, MD, MS, James M. Isbell, MD, MSCI, Daniel P

Robert C King, MD, Victor E Laubach, PhD, R

Use of Amiodarone After Major Lung Resection

Modified Ross Procedure to Prevent Autograft Dilatation

Thomas S. Maxey, MD, Christopher D. Smith, MBBS, John A

Impact of Blood Product Transfusion on Short and Long-Term Survival After Cardiac Surgery: More Evidence Balu Bhaskar, MD, FCICM, Joel Dulhunty, PhD,

Abel Gómez-Caro, MD, Pedro Arguis, MD The Annals of Thoracic Surgery

Aditya K. Kaza, MD The Journal of Thoracic and Cardiovascular Surgery

Patient Preferences in Treatment Choices for Early-Stage Lung Cancer

Eric S. Weiss, MD, MPH, Jeremiah G. Allen, MD, Christian A

Percutaneous Transcatheter Closure of the Aortic Valve

Kyle H. Cichos, BS, Paul L. Linsky, MD, Benjamin Wei, MD, Douglas J

William M. Whited, MD, Paul Henley, BS, Erin M

Completely Thrombosed Tricuspid Pouch Mimicking a Cardiac Tumor

Daniel P. Mulloy, MD, Ashish K. Sharma, MBBS, PhD, Lucas G

Kenan W. Yount, MD MBA, Leora T. Yarboro, MD, Adishesh K

An Unusual Cause of Hemoptysis in a Young Woman

The Annals of Thoracic Surgery

Does Morbid Obesity Worsen Outcomes After Esophagectomy?

Anirudh Vinnakota, MS, Robert Stewart, MD, Gosta Pettersson, MD, PhD

Sequential Design for Clinical Trials Evaluating a Prosthetic Heart Valve Cody Hamilton, PhD, Michael Lu, PhD, Steven Lewis, PhD, William Anderson, PhD

Specialty Training and Mortality After Esophageal Cancer Resection

Scott B. Johnson, MD, Anna M. Allred, BS, Adam M. Cline, MD, Luis F

Dana Y. Fuhrman, DO, MS, Lan G

Invited Commentary The Annals of Thoracic Surgery

Functional and Physiologic Results of Video-Assisted Thoracoscopic Diaphragm Plication in Adult Patients With Unilateral Diaphragm Paralysis Richard.

Robert Lee Replogle, September 30, 1931–May 9, 2016

Digital Drainage System Reduces Hospitalization After Video-Assisted Thoracoscopic Surgery Lung Resection Daniel L. Miller, MD, Gerald A. Helms, MD,

The American Board of Thoracic Surgery: Update

Gorav Ailawadi, MD, Damien J. LaPar, MD, Brian R

“Transitions” for Cardiothoracic Surgeons Now Listed on the Web:

Reevaluating the Need for Left Subclavian Artery Revascularization With Thoracic Endovascular Aortic Repair T. Brett Reece, MD, Leo M. Gazoni, MD, Kenneth.

Lobectomy for Lung Cancer at Veterans Administration Medical Center Versus Academic Medical Center Travis Geraci, MD, Vanessa Baratta, MD, John Young,

Are There Enough Jobs in Cardiothoracic Surgery

Lucas G. Fernandez, MD, DSc, Timothy D

Experience With Bovine Pericardium for the Reconstruction of the Aortic Arch in Patients Undergoing a Norwood Procedure Victor O. Morell, MD, Peter A.

Joshua D. Adams, MD, Lynn M. Fedoruk, MD, Carlos A

Mark I. Block, MD The Annals of Thoracic Surgery

Contralateral Pulmonary Embolism Caused by Pulmonary Artery Stump Thrombosis After Pneumonectomy Wakana Sato, MD, Hiroyuki Watanabe, MD, PhD, Teruki.

Late Consequences of a Much Earlier Decision

Lobectomy Versus Limited Resection in T1N0 Lung Cancer

The Impact of New Technology on Cardiothoracic Surgical Practice

John R. Handy, MD, HonD, Kelly Denniston, RHIT, Gary L

Domenico Galetta, MD, PhD, Lorenzo Spaggiari, MD, PhD

When to discontinue extracorporeal membrane oxygenation for postcardiotomy support Steven M Fiser, MD, Curtis G Tribble, MD, Aditya K Kaza, MD, Stewart.

J. Alberto Lopez, MD The Annals of Thoracic Surgery

Presentation transcript:

Retinoic acid enhances lung growth after pneumonectomy Aditya K Kaza, MD, Irving L Kron, MD, John A Kern, MD, Stewart M Long, MD, Steven M Fiser, MD, Richard P Nguyen, BS, Curtis G Tribble, MD, Victor E Laubach, PhD The Annals of Thoracic Surgery Volume 71, Issue 5, Pages 1645-1650 (May 2001) DOI: 10.1016/S0003-4975(01)02478-X Copyright © 2001 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Initial and final total body weight (iTBW and fTBW) at 10- and 21-day intervals. ∗p = 0.007 for iTBW versus fTBW. (P = pneumonectomy; R = pneumonectomy with administration of retinoic acid; S = sham thoracotomy.) The Annals of Thoracic Surgery 2001 71, 1645-1650DOI: (10.1016/S0003-4975(01)02478-X) Copyright © 2001 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Lung volume index at 10- and 21-day intervals. @p < 0.001 versus S10; ∗p < 0.001 versus S10 and P10; &p < 0.001 versus S21; #p < 0.001 versus S21 and P21. (P = pneumonectomy; R = pneumonectomy with administration of retinoic acid; S = sham thoracotomy.) The Annals of Thoracic Surgery 2001 71, 1645-1650DOI: (10.1016/S0003-4975(01)02478-X) Copyright © 2001 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Lung weight index at 10- and 21-day intervals. ∗p < 0.001 versus S10 and P10; @p < 0.001 versus S21; #p < 0.001 versus S21 and P21. (P = pneumonectomy; R = pneumonectomy with administration of retinoic acid; S = sham thoracotomy.) The Annals of Thoracic Surgery 2001 71, 1645-1650DOI: (10.1016/S0003-4975(01)02478-X) Copyright © 2001 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Cellular proliferation index (% of dividing cells) at 21-day interval. #p < 0.001 versus S21; ∗p < 0.001 versus S21 and P21. (P = pneumonectomy; R = pneumonectomy with administration of retinoic acid; S = sham thoracotomy.) The Annals of Thoracic Surgery 2001 71, 1645-1650DOI: (10.1016/S0003-4975(01)02478-X) Copyright © 2001 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Western blot analysis for the detection of epidermal growth factor receptor (EGFR) at 21 days. The Western blot is shown at top (EGFR, 170kDa). The computerized densitometry is shown below. ∗p = 0.017 versus S21 and P21. (P = pneumonectomy; R = pneumonectomy with administration of retinoic acid; S = sham thoracotomy.) The Annals of Thoracic Surgery 2001 71, 1645-1650DOI: (10.1016/S0003-4975(01)02478-X) Copyright © 2001 The Society of Thoracic Surgeons Terms and Conditions