Validation of Clinical Testing for Warfarin Sensitivity

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Presentation transcript:

Validation of Clinical Testing for Warfarin Sensitivity Michael R. Langley, Jessica K. Booker, James P. Evans, Howard L. McLeod, Karen E. Weck The Journal of Molecular Diagnostics Volume 11, Issue 3, Pages 216-225 (May 2009) DOI: 10.2353/jmoldx.2009.080123 Copyright © 2009 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 1 Comparison of four algorithms for determining warfarin dosage. Shown is the actual mean warfarin dose (mg/day) plotted against the warfarin dose predicted by each of the dosing algorithms for patients on long-term, stable warfarin therapy (n = 75). Blue diamonds represent each patient analyzed. Red squares represent outlier patients with high warfarin doses not predicted by any of the dosing algorithms. For each graph, solid dark lines represent the best-fit trendline plotted in Excel using linear regression and dashed light lines represent the line of identity. The linear correlation coefficient (r) for each algorithm is shown. The Journal of Molecular Diagnostics 2009 11, 216-225DOI: (10.2353/jmoldx.2009.080123) Copyright © 2009 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions