Volume 54, Issue 4, Pages (October 1998)

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Volume 54, Issue 4, Pages 1283-1289 (October 1998) Effects of an ACE inhibitor/calcium antagonist combination on proteinuria in diabetic nephropathy  George L. Bakris, Matthew R. Weir, Vincent Dequattro, F. Gilbert McMahon  Kidney International  Volume 54, Issue 4, Pages 1283-1289 (October 1998) DOI: 10.1046/j.1523-1755.1998.00083.x Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 1 Protocol of blood pressure measured monthly.*GFR and 24-hour urinary excretion of protein, albumin, creatinine, β2-microglobulin and sodium were measured every three months. Abbreviations are: T, trandolapril, V, verapamil SR; T/V, trandolapril + verapamil SR. Kidney International 1998 54, 1283-1289DOI: (10.1046/j.1523-1755.1998.00083.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 2 Mean arterial pressure in each group over the one year duration of the study. Abbreviations are: T, trandolapril; V, verapamil SR; T/V, trandolapril + verapamil SR. Symbols are: (□) V; (⋄) T; (▴) T+V. *P < 0.05 compared to either V alone or T alone. Kidney International 1998 54, 1283-1289DOI: (10.1046/j.1523-1755.1998.00083.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 3 The percent reduction from baseline in both proteinuria (▪) and mean arterial pressure () at one year. Abbreviation T/V is trandolapril + verapamil SR.#P < 0.05 difference between albuminuria reduction and MAP in a given group. *P < 0.05 different from other groups of albuminuria reduction. Kidney International 1998 54, 1283-1289DOI: (10.1046/j.1523-1755.1998.00083.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 4 Trends in proteinuria over the one year study. Abbreviations are: T, trandolapril; V, verapamil SR; T/V, trandolapril + verapamil SR. Symbols are: (□) V; (⋄) T; (▴) T+V.*P < 0.05 compared to T or V alone. Kidney International 1998 54, 1283-1289DOI: (10.1046/j.1523-1755.1998.00083.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, 1283-1289DOI: (10. 1046/j. 1523-1755 Kidney International 1998 54, 1283-1289DOI: (10.1046/j.1523-1755.1998.00083.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, 1283-1289DOI: (10. 1046/j. 1523-1755 Kidney International 1998 54, 1283-1289DOI: (10.1046/j.1523-1755.1998.00083.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, 1283-1289DOI: (10. 1046/j. 1523-1755 Kidney International 1998 54, 1283-1289DOI: (10.1046/j.1523-1755.1998.00083.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, 1283-1289DOI: (10. 1046/j. 1523-1755 Kidney International 1998 54, 1283-1289DOI: (10.1046/j.1523-1755.1998.00083.x) Copyright © 1998 International Society of Nephrology Terms and Conditions