Reproductive BioMedicine Online

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Reproductive BioMedicine Online A multicentre evaluation of the Elecsys® anti-Müllerian hormone immunoassay for prediction of antral follicle count Michael H. Jacobs, Laura M. Reuter, Valerie L. Baker, LaTasha B. Craig, Denny Sakkas, Eric Surrey, Kevin J. Doody, Emily S. Jungheim, Aykut B. Bayrak, Martin Hund, Wilma D.J. Verhagen-Kamerbeek, Deborah Pardue, Katharina Buck, Barbara Timm Reproductive BioMedicine Online DOI: 10.1016/j.rbmo.2018.12.041 Copyright © 2019 Roche Diagnostics Ltd Terms and Conditions

Figure 1 Patient flow diagram. BMI = body mass index; HCG = human chorionic gonadotrophin. Reproductive BioMedicine Online DOI: (10.1016/j.rbmo.2018.12.041) Copyright © 2019 Roche Diagnostics Ltd Terms and Conditions

Figure 2 Summary of AMH by AFC class (0–15 versus >15) per study cohort (derivation, validation and overall cohort). AFC = antral follicle count; AMH = anti-Müllerian hormone. Reproductive BioMedicine Online DOI: (10.1016/j.rbmo.2018.12.041) Copyright © 2019 Roche Diagnostics Ltd Terms and Conditions

Figure 3 ROC curve for prediction of AFC >15 by AMH, FSH and oestradiol in (A) the derivation cohort (n = 306) and (B) the validation cohort (n = 856). AFC = antral follicle count; AMH = anti-Müllerian hormone; AUC = area under curve; E2 = estradiol; FSH = follicle-stimulating hormone; ROC = receiver operating characteristic. Reproductive BioMedicine Online DOI: (10.1016/j.rbmo.2018.12.041) Copyright © 2019 Roche Diagnostics Ltd Terms and Conditions