Virulence determinants in California S. sonnei isolates.

Slides:

Advertisements

Similar presentations

Requisites for Successful Growth Attachment Nutrition Survival from host defence Transmission.

Advertisements

Regulation of Virulence Genes Salyers & Whitt: Bacterial Pathogenesis: A Molecular Approach ASM Press, 1994 Dorman, C.J: Genetics of Bacterial Virulence.

Escherichia coli O157:H7 and Shiga toxin-converting bacteriophage Edward G. Dudley, Ph.D Department of Food Science

Lecture 1: Metabolism and Assembly Reactions Reading assignments in Text: Lengeler et al Text:pages Metabolic overview Text:pages ,

Dr Sabrina Moyo Department of Microbiology and Immunology

Prof. Khalifa Sifaw Ghenghesh Dept. of Medical Microbiology, Faculty of Medicine, Tripoli University, Tripoli-Libya بسم الله الرحمن الرحيم BACTERIAL PATHOGENESIS.

SHIGELLA By: Hunter Reynolds.

Chapter 17 Host- Microbe Interaction Biology 261 Medgar Evers College, CUNY Prof. Santos.

Bacteria-Host Relationships commensals opportunistic pathogens primary pathogens.

Shigella sonnei Antimicrobial Resistance, Phage Typing And Molecular Characterisation Niall DeLappe 1, D.Morris 2, S.Fanning 3, M.Daly 3, T.Chiesty 4,

ESCHERICHIA COLI DON XAVIER N.D. MORPHOLOGY Gram negative, Oxidase Negative Non sporing, Non capsulated bacillus. Strains of E.coli are usually motile.

Chapter 16 Host- Microbe Interaction

Table 2. List of the test pathogenic bacteria

Host- Microbe Interactions

Shigella-specific serum IgG and IgA endpoint titers in guinea pigs immunized intranasally with S. flexneri 2a InvaplexNAT or InvaplexAR. Shigella-specific.

Expression levels of additional giardia genes in elutriation fractions

Virulence of aggregate-forming and nonaggregate strains of Candida auris compared to C. albicans in Galleria mellonella larvae at 30°C (upper panel) and.

SEC-HPLC of InvaplexNAT and InvaplexAR.

Lysis of shiga toxin-producing Escherichia coli by delivery of Crispr/Cas9 cascade coding cosmid targeting Stx 1 and Stx 2 genes via lambda phage delivery.

Validation of Tn-seq fitness defects in rich and defined media.

DNSP16 mutation attenuates the virulence of a mouse-adapted MERS-CoV strain. dNSP16 mutation attenuates the virulence of a mouse-adapted MERS-CoV strain.

Predicted location and functional classification of differentially expressed transcripts. Predicted location and functional classification of differentially.

Fold change differences for each bacterial genus in the two fraction pairs. Fold change differences for each bacterial genus in the two fraction pairs.

Phylogeny of Shiga toxin-encoding phage from SDi/SJo S. sonnei isolates. Phylogeny of Shiga toxin-encoding phage from SDi/SJo S. sonnei isolates. (A) progressiveMauve.

Isolation and phylogenetic characterization of ISS strains.

Comparison of the variable regions of (A) pHNZY32, pHNZY118, and pHNAH24; (B) pHNMCC14; (C) pHNFKU92; (D) pE80; (E) pECB11; (F) p42-2; and (G) pSLK172-2.

Flow sheet over the primary study population as well as comparative individuals of “pre-diabetic” individuals followed from HUNT2 to HUNT3 (GAD, glutamic.

Expression response of AT-rich genes to lanthanides.

The virulence of Candida species in Galleria mellonella larvae at 37°C is species specific. The virulence of Candida species in Galleria mellonella larvae.

Assembly of the novel bat gammaherpesvirus genome highlights ORFs related to EHV-2 and accessory ORFs related to other gammaherpesviruses. Assembly of.

Manders colocalization coefficient (MCC) values quantify the different levels of colocalization between TRP75 and interacting host proteins in E. chaffeensis-infected.

Comparative analysis of Aeromonas sp.

Subcellular localization of UUKV, HRTV, and SFTSV NSs

Genes involved in EPEC pathogenesis.

KEGG pathway analysis of the C

Relative growth of WT R2866 and the R2866ΔampG gene deletion mutant with Triton X-100. Relative growth of WT R2866 and the R2866ΔampG gene deletion mutant.

Chromosomally expressed RΔ-CTB is poorly immunogenic.

RNA-Seq analysis of CYR1 cells in the adaptation to acid pH.

C. difficile colonization alters gene transcription of taxonomic groups differentially between antibiotic pretreatments. C. difficile colonization alters.

Dynamic ranges of anti-PnPS IgG Reference standard serum 007sp for each of 13 serotypes. Dynamic ranges of anti-PnPS IgG Reference standard serum 007sp.

Growth of Salmonella and E. coli in egg white.

General structure of RIFINs and STEVORs

Dynamic light scattering (DLS) analysis of S

Minor variants expand the range of neonatal HSV-2 coding diversity.

A proximal region of the G6Pase catalytic subunit promoter is sufficient for maximal basal reporter gene expression in HIT cells. A proximal region of.

OVA-specific and InvaplexNAT-specific serum IgG endpoint titers in mice after intranasal immunization with OVA alone or OVA combined with InvaplexAR, InvaplexNAT,

Schematic representation of the involvement of each of the four genes on virulence factor expression. Schematic representation of the involvement of each.

ToxT production profiles of single-SNP strains and double-, triple-, and quadruple-SNP combination strains. ToxT production profiles of single-SNP strains.

Most mutations were nonsynonymous, especially at the nodes of new clades, with affected genes encoding regulatory functions, lipid metabolism, and envelope.

SAM transport by Gap4 in S. cerevisiae cells.

Bacterial composition of olive fermentations is affected by microbial inoculation. Bacterial composition of olive fermentations is affected by microbial.

ITS rRNA gene locus. ITS rRNA gene locus. Schematic of the eukaryotic ribosomal gene cluster. The SILVA database contains sequences of the 18S gene, while.

CozE homologs do not dramatically affect cell division in L. plantarum

KEGG cluster of DEGs of S

A. baumannii stimulates the autophagy.

OMV-enriched proteins show a conserved N-terminal LES motif.

Intranasal immunization of mice with S

TcpA production profiles of single-SNP strains and double-, triple-, and quadruple-SNP combination strains. TcpA production profiles of single-SNP strains.

CT production profiles of single-SNP strains and double-, triple-, and quadruple-SNP combination strains. CT production profiles of single-SNP strains.

Distribution of the diversity numbers of antibiotic resistance and virulence factor protein families by environmental metagenomes’ protein family richness.

Characteristics of ADs from S. cerevisiae S288C.

Normalized abundance of tetracycline resistance genes in Swedish infants by AMR++. Normalized abundance of tetracycline resistance genes in Swedish infants.

Transient CRISPR-Cas9 system.

DNase and proteinase K treatment of WT R2866 and R2866ΔampG gene deletion mutant biofilms. DNase and proteinase K treatment of WT R2866 and R2866ΔampG.

Phylogenetic analysis of complete Fusobacterium genomes.

Total ARG reads normalized by read length and 16S gene read count in early life in Bangladesh. Total ARG reads normalized by read length and 16S gene read.

Sequence alignment of colicin lysis proteins.

Normalized weight gain of protein-sufficient and -deficient HRV-infected pigs transplanted with sufficient and deficient HIFM (sHIFM/dHIFM) and monitored.

Expression levels of additional giardia genes in elutriation fractions

Confirmation of spliced RNA in cells transfected with a wild-type or Pol(−) MR766 ZIKV plasmid. Confirmation of spliced RNA in cells transfected with a.

Presentation transcript:

Virulence determinants in California S. sonnei isolates. Virulence determinants in California S. sonnei isolates. Virulence determinants: stx1A, Shiga toxin 1, subunit A, variant a; stx1B, Shiga toxin 1, subunit B, variant a; sigA, Shigella IgA-like protease homolog; gad, glutamate decarboxylase; ipaH9.8, invasion plasmid antigen; senB, plasmid-encoded enterotoxin; prfB, P-related fimbriae regulatory gene; lpfA, long polar fimbriae; celb, endonuclease colicin E2; ipaD, invasion protein S. flexneri; virF, VirF transcriptional activator; iss, increased serum survival; sat, secreted autotransporter toxin. Varvara K. Kozyreva et al. mSphere 2016; doi:10.1128/mSphere.00344-16