Very long-term clinical outcomes after radiofrequency catheter ablation for atrial fibrillation: A large single-center experience Tetsuma Kawaji, Satoshi.

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Very long-term clinical outcomes after radiofrequency catheter ablation for atrial fibrillation: A large single-center experience Tetsuma Kawaji, Satoshi Shizuta, Takeshi Morimoto, Takanori Aizawa, Shintaro Yamagami, Takashi Yoshizawa, Chihiro Ota, Naoaki Onishi, Yasuhiro Sasaki, Mitsuhiko Yahata, Kentaro Nakai, Mamoru Hayano, Tetsushi Nakao, Koji Hanazawa, Koji Goto, Takahiro Doi, Koh Ono, Takeshi Kimura International Journal of Cardiology Volume 249, Pages 204-213 (December 2017) DOI: 10.1016/j.ijcard.2017.09.023 Copyright © 2017 The Authors Terms and Conditions

Fig. 1 Event-free survival from recurrent atrial tachyarrhythmias. Event-free survival from recurrent atrial tachyarrhythmias with a blanking period of 90days; (A) after the initial procedure, (B) after the last procedure, (C) after the initial procedure according to AF type, and (D) after the last procedure according to AF type. AF=atrial fibrillation, LlAF=long-lasting AF, PAF=paroxysmal AF, and PeAF=persistent AF. International Journal of Cardiology 2017 249, 204-213DOI: (10.1016/j.ijcard.2017.09.023) Copyright © 2017 The Authors Terms and Conditions

Fig. 2 Survival-free curves from clinical outcomes during follow-up. Survival-free curves from all-cause death and cardiovascular death in the entire population (A) and those from all cause death according to AF type (B). Survival-free curves from heart failure hospitalization in the entire population (C) and in patients stratified according to AF type (D). Survival-free curves from stroke in the entire population (E) and in patients stratified according to AF type (F). Survival-free curves from major bleeding in the entire population (G) and in patients stratified according to AF type (H). AF=atrial fibrillation, LlAF=long-lasting AF, PAF=paroxysmal AF, and PeAF=persistent AF. International Journal of Cardiology 2017 249, 204-213DOI: (10.1016/j.ijcard.2017.09.023) Copyright © 2017 The Authors Terms and Conditions

Fig. 2 Survival-free curves from clinical outcomes during follow-up. Survival-free curves from all-cause death and cardiovascular death in the entire population (A) and those from all cause death according to AF type (B). Survival-free curves from heart failure hospitalization in the entire population (C) and in patients stratified according to AF type (D). Survival-free curves from stroke in the entire population (E) and in patients stratified according to AF type (F). Survival-free curves from major bleeding in the entire population (G) and in patients stratified according to AF type (H). AF=atrial fibrillation, LlAF=long-lasting AF, PAF=paroxysmal AF, and PeAF=persistent AF. International Journal of Cardiology 2017 249, 204-213DOI: (10.1016/j.ijcard.2017.09.023) Copyright © 2017 The Authors Terms and Conditions

Fig. 3 Cumulative incidence of OAC discontinuation. Cumulative incidence of OAC discontinuation in the entire population (A), in patients stratified according to AF type (B), and in patients stratified according to CHA2DS2-VASC score (C). AF=atrial fibrillation, LlAF=long-lasting AF, PAF=paroxysmal AF, and PeAF=persistent AF. International Journal of Cardiology 2017 249, 204-213DOI: (10.1016/j.ijcard.2017.09.023) Copyright © 2017 The Authors Terms and Conditions

Fig. 4 Details of ischemic stroke and major bleeding. A) Pathogenesis of ischemic stroke and source of major bleeding, and B) antithrombotic therapy at the time of events. DAPT=dual antiplatelet therapy, SAPT=single antiplatelet therapy, OAC=oral anticoagulation. International Journal of Cardiology 2017 249, 204-213DOI: (10.1016/j.ijcard.2017.09.023) Copyright © 2017 The Authors Terms and Conditions