Design of the trial. Design of the trial. (1) Patients with advanced recurrent pancreatic cancer aged ≥75 years, (2) unresectable/recurrence, (3) -performance.

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Presentation transcript:

Design of the trial. Design of the trial. (1) Patients with advanced recurrent pancreatic cancer aged ≥75 years, (2) unresectable/recurrence, (3) -performance status 0–1, (4) randomisation, (5) allocation adjustment factors: institution, disease stage, CA19-9, (6) group A: GEM therapy alone, (7) GEM 1000 mg/m2, (8) days 1, 8 and 15 for 4 weeks, (9) group B: GS therapy, (10) GEM 1000 mg/m2, (11) days 1 and 8 for 3 weeks, (12) S-1 65 mg/m2/day 1–14. (13) Treatment will be continued until the condition meets the discontinuation criteria of the protocol treatment. GEM, gemcitabine hydrochloride; GS, gemcitabine hydrochloride + S-1. Hiroshi Ishii et al. BMJ Open Gastroenterol 2018;5:e000187 © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.