Asians with cystic fibrosis in the UK have worse disease outcomes than clinic matched white homozygous ΔF508 controls Jonathan McCormick, Simon A. Ogston,

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Presentation transcript:

Asians with cystic fibrosis in the UK have worse disease outcomes than clinic matched white homozygous ΔF508 controls Jonathan McCormick, Simon A. Ogston, Erika J. Sims, Anil Mehta Journal of Cystic Fibrosis Volume 4, Issue 1, Pages 53-58 (March 2005) DOI: 10.1016/j.jcf.2004.11.003 Copyright © 2004 European Cystic Fibrosis Society Terms and Conditions

Fig. 1 Mean differences in FEV1% predicted between Asian patients and controls for male (squares) and female (circles). Data based on 21 male Asian CF patients with 52 matched controls, and 14 female Asian CF patients with 29 matched control patients. No difference between Asians and controls is represented by the dotted line. FEV1% predicted calculations: unadjusted (as per Polgar/Cherniak, filled symbols), ethnicity adjustment (BTS/ARTP, unfilled symbols) and malnourishment adjustment (Ong, grey symbols). Journal of Cystic Fibrosis 2005 4, 53-58DOI: (10.1016/j.jcf.2004.11.003) Copyright © 2004 European Cystic Fibrosis Society Terms and Conditions

Fig. 2 Mean differences in FVC% predicted between Asian patients and controls for male (squares) and female (circles). Data based on 21 male Asian CF patients with 52 matched controls, and 14 female Asian CF patients with 29 matched control patients. The dotted line represents no difference between the Asian and Caucasian groups. Filled and unfilled symbols represent data unadjusted and adjusted for ethnicity, respectively. Journal of Cystic Fibrosis 2005 4, 53-58DOI: (10.1016/j.jcf.2004.11.003) Copyright © 2004 European Cystic Fibrosis Society Terms and Conditions

Fig. 3 Mean differences in height, weight and BMI Z scores between active Asian patients and Caucasian homozygous ΔF508 controls, with and without adjustment for ethnicity. Squares=males, circles=female. Data based on 30 male Asian CF patients with 92 matched controls, and 20 female Asian CF patients with 51 matched controls. The dotted line represents no difference between the Asian and Caucasian groups. Filled and unfilled symbols represent data unadjusted and adjusted for ethnicity, respectively. Journal of Cystic Fibrosis 2005 4, 53-58DOI: (10.1016/j.jcf.2004.11.003) Copyright © 2004 European Cystic Fibrosis Society Terms and Conditions