D. J. Hunter, D. P. Beavers, F. Eckstein, A. Guermazi, R. F. Loeser, B

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Presentation transcript:

The Intensive Diet and Exercise for Arthritis (IDEA) trial: 18-month radiographic and MRI outcomes D.J. Hunter, D.P. Beavers, F. Eckstein, A. Guermazi, R.F. Loeser, B.J. Nicklas, S.L. Mihalko, G.D. Miller, M. Lyles, P. DeVita, C. Legault, J.J. Carr, J.D. Williamson, S.P. Messier Osteoarthritis and Cartilage Volume 23, Issue 7, Pages 1090-1098 (July 2015) DOI: 10.1016/j.joca.2015.03.034 Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Landmarks and definition of coordinate system. Osteoarthritis and Cartilage 2015 23, 1090-1098DOI: (10.1016/j.joca.2015.03.034) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 (a) Sagittal magnetic resonance images (MRI) acquired using SPGR sequence. Both images depict the same slice of the MFTC. The image on the right shows the segmentation of the cartilage (magenta = segmentation of the cartilage surface; green = segmentation of the total area of subchondral bone = tAB) and the filling between the two surfaces in turquoise. The image of the MFTC shows an area of denuded subchondral bone (dAB) in the weight-bearing aspect of the medial femoral condyle (cMF) and medial tibia (MT). (b) Visual display of the medial femorotibial subregions. Posterior view of the femorotibial compartment of the knee (middle), inferior view of the weight-bearing femur (top), and superior view of the tibia (bottom). Color codes for both the femoral and tibial plates: red = central subregion, green = external subregion, blue = internal subregion, yellow = posterior subregion, turqoise = anterior subregion. Osteoarthritis and Cartilage 2015 23, 1090-1098DOI: (10.1016/j.joca.2015.03.034) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Percent changes from baseline (95% CI) for mJSW and MTFC thickness. Osteoarthritis and Cartilage 2015 23, 1090-1098DOI: (10.1016/j.joca.2015.03.034) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions