Volume 16, Issue 1, Pages 9-13 (June 2009) l-Arginine supplementation enhances eNOS expression in experimental model of hypercholesterolemic rabbits aorta  Shaghayegh Haghjooy Javanmard, Mehdi Nematbakhsh, Farzaneh Mahmoodi, Mohamad Reza Mohajeri  Pathophysiology  Volume 16, Issue 1, Pages 9-13 (June 2009) DOI: 10.1016/j.pathophys.2008.11.003 Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 H&E staining of rabbits aortas showed the formation of fatty streak lesions in the first group of experiment after 4 weeks of 1% cholesterol diet (A) while there were no fatty streaks in group (B) receiving additionally l-arginine in drinking water. Pathophysiology 2009 16, 9-13DOI: (10.1016/j.pathophys.2008.11.003) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Immunohistochemical eNOS and iNOS protein expressions in aorta of cholesterol-fed rabbits. The aortic segments isolated from hypercholesterolemic and l-arginine-treated animals (group 2) showed higher eNOS expression (A) than hypercholesterolemic animals without dietary l-arginine (group1) (B). There was a trend toward decreased expression of iNOS in hypercholesterolemic and l-arginine-treated animals (C) compare to hypercholesterolemic animals without dietary l-arginine (D). Pathophysiology 2009 16, 9-13DOI: (10.1016/j.pathophys.2008.11.003) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions