Rajasekhara R. Mummadi, Krishna S

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Presentation transcript:

Effect of Bariatric Surgery on Nonalcoholic Fatty Liver Disease: Systematic Review and Meta-Analysis  Rajasekhara R. Mummadi, Krishna S. Kasturi, Swapna Chennareddygari, Gagan K. Sood  Clinical Gastroenterology and Hepatology  Volume 6, Issue 12, Pages 1396-1402 (December 2008) DOI: 10.1016/j.cgh.2008.08.012 Copyright © 2008 AGA Institute Terms and Conditions

Figure 1 Study attrition diagram. Clinical Gastroenterology and Hepatology 2008 6, 1396-1402DOI: (10.1016/j.cgh.2008.08.012) Copyright © 2008 AGA Institute Terms and Conditions

Figure 2 Forest plot showing improvement or resolution of steatosis after bariatric surgical procedures. The left-hand column in the Forest plot lists the names of the studies. The squares on the right-hand column indicate the effect measure (proportion of patients with response). The horizontal lines that cut through the squares indicate CIs. The size of each square is proportional to the study's weight in the meta-analysis. The diamond represents the meta-analyzed effect measure and the horizontal lines indicate the confidence interval. Available from: http://en.wikipedia.org/wiki/Forest_plot. Accessed: July 22, 2008. I2 (inconsistency) = 91.8% (95% CI, 88.6%–93.7%). Random effects (DerSimonian-Laird): pooled proportion = 91.6% (95% CI, 82.4%–97.6%). Clinical Gastroenterology and Hepatology 2008 6, 1396-1402DOI: (10.1016/j.cgh.2008.08.012) Copyright © 2008 AGA Institute Terms and Conditions

Figure 3 Forest plot showing improvement or resolution of steatohepatitis after bariatric surgical procedures: I2 (inconsistency) = 91.6% (95% CI, 86.9%–94.1%). Random effects (DerSimonian-Laird): pooled proportion = 81.3% (95% CI, 61.9%–94.9%). Clinical Gastroenterology and Hepatology 2008 6, 1396-1402DOI: (10.1016/j.cgh.2008.08.012) Copyright © 2008 AGA Institute Terms and Conditions

Figure 4 Forest plot showing complete resolution of steatohepatitis after bariatric surgical procedures: I2 (inconsistency) = 94.4% (95% CI, 92%–95.9%). Random effects (DerSimonian-Laird): pooled proportion = 69.5% (95% CI, 42.4%–90.8%). Clinical Gastroenterology and Hepatology 2008 6, 1396-1402DOI: (10.1016/j.cgh.2008.08.012) Copyright © 2008 AGA Institute Terms and Conditions

Figure 5 Forest plot showing improvement or resolution of fibrosis (subgroup analysis using studies with needle biopsies only) after bariatric surgical procedures: I2 (inconsistency) = 88.8% (95% CI, 75%–93.5%). Random effects (DerSimonian-Laird): pooled proportion = 65.5% (95% CI, 38.2%–88.1%). Clinical Gastroenterology and Hepatology 2008 6, 1396-1402DOI: (10.1016/j.cgh.2008.08.012) Copyright © 2008 AGA Institute Terms and Conditions