O. Hamzaoui, M. Jozwiak, T. Geffriaud, B. Sztrymf, D. Prat, F

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Norepinephrine exerts an inotropic effect during the early phase of human septic shock O. Hamzaoui, M. Jozwiak, T. Geffriaud, B. Sztrymf, D. Prat, F. Jacobs, X. Monnet, P. Trouiller, C. Richard, J.L. Teboul British Journal of Anaesthesia Volume 120, Issue 3, Pages 517-524 (March 2018) DOI: 10.1016/j.bja.2017.11.065 Copyright © 2017 Terms and Conditions

Fig 1 Box-and-whisker plots of left ventricular ejection fraction (LVEF; A), velocity-time integral of the flow of the left ventricular outflow tract (VTI; B), tissue Doppler imaging of the systolic motion of the tricuspid annulus (Sa; C), tricuspid annular plane systolic excursion (TAPSE; D), and tissue Doppler imaging of mean systolic velocity of the mitral annulus (Sm; E) before (T0) and after (T1) restoration of a mean arterial pressure >65 mm Hg with norepinephrine in the whole population (n=38). *P<0.05. British Journal of Anaesthesia 2018 120, 517-524DOI: (10.1016/j.bja.2017.11.065) Copyright © 2017 Terms and Conditions

Fig 2 Individual responses of left ventricular ejection fraction (LVEF; A) and velocity-time integral of the sub-aortic flow (VTI; B) before (T0) and after (T1) restoration of a mean arterial pressure >65 mm Hg with norepinephrine in patients with an LVEF <45% at T0 (n=15). British Journal of Anaesthesia 2018 120, 517-524DOI: (10.1016/j.bja.2017.11.065) Copyright © 2017 Terms and Conditions