S. Hagihira British Journal of Anaesthesia

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Changes in the electroencephalogram during anaesthesia and their physiological basis S. Hagihira British Journal of Anaesthesia Volume 115, Pages i27-i31 (July 2015) DOI: 10.1093/bja/aev212 Copyright © 2015 The Author(s) Terms and Conditions

Fig 1 EEG waveform (4 s duration) during 0.3, 0.6, 0.9, 1.2, and 1.5% isoflurane anaesthesia in a 55-year-old ovarian tumor patient undergoing resection. British Journal of Anaesthesia 2015 115, i27-i31DOI: (10.1093/bja/aev212) Copyright © 2015 The Author(s) Terms and Conditions

Fig 2 Power spectrum changes during isoflurane anaesthesia in a 43-year-old female patient undergoing resection for colon cancer. British Journal of Anaesthesia 2015 115, i27-i31DOI: (10.1093/bja/aev212) Copyright © 2015 The Author(s) Terms and Conditions

Fig 3 Relative β ratio (RBR) changes during isoflurane anaesthesia. RBR values were calculated from stored data used in a previous report. (Source: ref.8). British Journal of Anaesthesia 2015 115, i27-i31DOI: (10.1093/bja/aev212) Copyright © 2015 The Author(s) Terms and Conditions

Fig 4 Scheme of neuronal circuits related to spindle generation GABA, gamma-amino butyric acid; Ach, acetylcholine; Glu, glutamate; PPT/LDT, pedunculopontine tegmental/laterodorsal tegmental nuclei. (Source: compiled from refs.10 11). British Journal of Anaesthesia 2015 115, i27-i31DOI: (10.1093/bja/aev212) Copyright © 2015 The Author(s) Terms and Conditions

Fig 5 Effect of surgical incision (noxious stimuli) on pBIC-high in 12 patients during isoflurane anaesthesia (Source: Plotter data from ref.13). British Journal of Anaesthesia 2015 115, i27-i31DOI: (10.1093/bja/aev212) Copyright © 2015 The Author(s) Terms and Conditions