Controls r=-0.82; P<0.0001 GHD r=-0.84; P<0.0001 Mean IMT (mm)

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Controls r=-0.82; P<0.0001 GHD r=-0.84; P<0.0001 Mean IMT (mm) Fig.2 Correlation analysis by calculating the Pearson coefficient between IGF-1 levels and mean intima-media thickness measured at the level of right and left common carotid arteries (top) and between IGF-1 levels and the total/HDL-cholesterol ratio in 39 healthy controls and in 39 patients diagnosed with severe GHD Controls r=-0.03; P<0.8 GHD r=-0.83; P<0.0001 Total/HDL-cholesterol ratio Serum IGF-1 levels (µg/l)‏ Abbildung mod. nach Colao, 2004

Mean IMT (mm)‏ GHD with normal IGF-1 GHD with low IGF-1 controls Fig. 3 Individual values of mean intima-media thickness measured at the level of right and left common carotid arteries in 19 patients with GHD and normal IGF-1 levels, 20 patients with GHD and low IGF-1levels for age and 39 healthy controls. *P<0,001 vs. Patients with GHD and normal IGF-1 levels ans vs. Controls Abbildung mod. nach Colao, 2004