Volume 4, Issue 3, Pages (March 2019)

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Volume 4, Issue 3, Pages 133-135 (March 2019) Endoscopic findings of checkpoint inhibitor–induced ileitis with use of the latest advanced endoscopic optical diagnosis: near-focus narrow-band imaging  Samuel C.L. Smith, MBChB, Davide Zardo, MD, Rosanna Cannatelli, MD, Neil Stevens, PhD, Marietta Iacucci, MD, PhD  VideoGIE  Volume 4, Issue 3, Pages 133-135 (March 2019) DOI: 10.1016/j.vgie.2018.11.005 Copyright © 2018 American Society for Gastrointestinal Endoscopy Terms and Conditions

Figure 1 Normal appearance of the cecum under high-definition white-light endoscopy. VideoGIE 2019 4, 133-135DOI: (10.1016/j.vgie.2018.11.005) Copyright © 2018 American Society for Gastrointestinal Endoscopy Terms and Conditions

Figure 2 High-definition white-light colonoscopic view showing granular and nonspecific appearances of the ileal mucosa. VideoGIE 2019 4, 133-135DOI: (10.1016/j.vgie.2018.11.005) Copyright © 2018 American Society for Gastrointestinal Endoscopy Terms and Conditions

Figure 3 Narrow-band image easily showing microerosions and hypertrophy of the villi. VideoGIE 2019 4, 133-135DOI: (10.1016/j.vgie.2018.11.005) Copyright © 2018 American Society for Gastrointestinal Endoscopy Terms and Conditions

Figure 4 Biopsy specimens from the ileum showing congested and edematous villi with otherwise preserved architecture (H&E, orig. mag. ×100). VideoGIE 2019 4, 133-135DOI: (10.1016/j.vgie.2018.11.005) Copyright © 2018 American Society for Gastrointestinal Endoscopy Terms and Conditions

Figure 5 Biopsy specimens from the ileum showing edematous villi with extravasated red blood cells (⇐) and scattered eosinophils (→) (H&E, orig. mag. ×200). VideoGIE 2019 4, 133-135DOI: (10.1016/j.vgie.2018.11.005) Copyright © 2018 American Society for Gastrointestinal Endoscopy Terms and Conditions

Figure 6 Biopsy specimens from the cecum showing a mild increase in eosinophils (→) (H&E, orig. mag. ×200). VideoGIE 2019 4, 133-135DOI: (10.1016/j.vgie.2018.11.005) Copyright © 2018 American Society for Gastrointestinal Endoscopy Terms and Conditions