Cross-sectional area for the calculation of carotid artery stenosis on computed tomographic angiography Anthony P. Carnicelli, BM, Jonathan J. Stone,

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Presentation transcript:

Cross-sectional area for the calculation of carotid artery stenosis on computed tomographic angiography Anthony P. Carnicelli, BM, Jonathan J. Stone, MD, Adam Doyle, MD, Amit K. Chowdhry, BS, Doran Mix, BS, Jennifer Ellis, MD, David L. Gillespie, MD, Ankur Chandra, MD Journal of Vascular Surgery Volume 58, Issue 3, Pages 659-665 (September 2013) DOI: 10.1016/j.jvs.2013.02.031 Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 1 Graphic representation of the variability between commonly used measurement techniques for evaluation of carotid artery stenosis. CT, Computed tomographic. Journal of Vascular Surgery 2013 58, 659-665DOI: (10.1016/j.jvs.2013.02.031) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 2 Top, Traditional North American Symptomatic Carotid Endarterectomy Trial (NASCET) method using diameter measurements to approximate carotid stenosis. Bottom, Investigational technique using cross-sectional area (CSA) measurements to approximate carotid stenosis. Journal of Vascular Surgery 2013 58, 659-665DOI: (10.1016/j.jvs.2013.02.031) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 3 Scatter plot demonstrating correlation between stenosis calculated from diameter measurements vs cross-sectional area (CSA) measurements. Journal of Vascular Surgery 2013 58, 659-665DOI: (10.1016/j.jvs.2013.02.031) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 4 Receiver-operating characteristic (ROC) curves demonstrating the ability of both diameter measurements (Diameter stenosis) and cross-sectional area measurements (CSA stenosis) to detect stenosis of >50%. Journal of Vascular Surgery 2013 58, 659-665DOI: (10.1016/j.jvs.2013.02.031) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 5 Receiver-operating characteristic (ROC) curves demonstrating the ability of both diameter measurements (Diameter stenosis) and cross-sectional area measurements (CSA stenosis) to detect stenosis of >80%. Journal of Vascular Surgery 2013 58, 659-665DOI: (10.1016/j.jvs.2013.02.031) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 6 Three-dimensional receiver-operating characteristic (ROC) surface plots depicting the ability of diameter measurements (A) and cross-sectional area (CSA) measurements (B) to characterize carotid stenosis. True fraction 1 describes the probability of the test correctly placing a patient in the <50% stenosis group; true fraction 2 likewise for the 50%-79% stenosis group; and true fraction 3 for the >80% stenosis group. Journal of Vascular Surgery 2013 58, 659-665DOI: (10.1016/j.jvs.2013.02.031) Copyright © 2013 Society for Vascular Surgery Terms and Conditions