Pulmonary 1, Case 6 56-year-old man with progressive dyspnea and bilateral infiltrates in lung.

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Presentation transcript:

Pulmonary 1, Case 6 56-year-old man with progressive dyspnea and bilateral infiltrates in lung.

Identify the organ Describe the gross morphologic changes Diagnosis?

Idiopathic pulmonary fibrosis Cut surface of lung with fibrosis and anthracosis

Compare to normal cut surface of lung

Identify the organ Describe the gross morphologic changes Diagnosis?

The cut surface of the lung reveals a "honeycomb" pattern of fibrosis. Pulmonary fibrosis The cut surface of the lung reveals a "honeycomb" pattern of fibrosis. The large air spaces are accentuated by the thick walls of fibrous tissue.

Interstitial fibrosis Fibrous tissue replacing normal lung parenchyma Large airspaces separated by bands of fibrous tissue

Fibrosis Alveolus lined by reactive pneumocytes