Efficacy and safety of budesonide inhalation suspension (Pulmicort Respules) in young children with inhaled steroid–dependent, persistent asthma Gail.

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Presentation transcript:

Efficacy and safety of budesonide inhalation suspension (Pulmicort Respules) in young children with inhaled steroid–dependent, persistent asthma Gail Shapiro, MDa, Louis Mendelson, MDb, Michael J. Kraemer, MDc, Mario Cruz-Rivera, PhD, MPHd, Karen Walton-Bowen, MSc, Cstatd, Joseph A. Smith, MDd Journal of Allergy and Clinical Immunology Volume 102, Issue 5, Pages 789-796 (November 1998) DOI: 10.1016/S0091-6749(98)70019-3 Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 1 Mean change from baseline nighttime (top panel) and daytime (bottom panel) asthma symptoms scores during treatment weeks 0 to 12. *P ≤ .05 versus placebo; ‡P ≤ .01 versus placebo. BID, Twice daily. Journal of Allergy and Clinical Immunology 1998 102, 789-796DOI: (10.1016/S0091-6749(98)70019-3) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 2 Mean change from baseline (± 95% confidence interval) in number of days bronchodilator (pMDI or nebulizer) was required over the 12-week treatment period. *P ≤ .05 versus placebo; †P ≤ .01 versus placebo. BID, Twice daily. Journal of Allergy and Clinical Immunology 1998 102, 789-796DOI: (10.1016/S0091-6749(98)70019-3) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 3 Mean basal and ACTH-stimulated cortisol levels (± SD) at baseline and after the 12-week treatment period for each group. BID, Twice daily. Journal of Allergy and Clinical Immunology 1998 102, 789-796DOI: (10.1016/S0091-6749(98)70019-3) Copyright © 1998 Mosby, Inc. Terms and Conditions