Diagnostic Performance of Measurement of Fecal Elastase-1 in Detection of Exocrine Pancreatic Insufficiency: Systematic Review and Meta-analysis Rohini.

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Presentation transcript:

Diagnostic Performance of Measurement of Fecal Elastase-1 in Detection of Exocrine Pancreatic Insufficiency: Systematic Review and Meta-analysis Rohini R. Vanga, Aylin Tansel, Saad Sidiq, Hashem B. El-Serag, Mohamed O. Othman Clinical Gastroenterology and Hepatology Volume 16, Issue 8, Pages 1220-1228.e4 (August 2018) DOI: 10.1016/j.cgh.2018.01.027 Copyright © 2018 AGA Institute Terms and Conditions

Figure 1 PRISMA flow diagram. Clinical Gastroenterology and Hepatology 2018 16, 1220-1228.e4DOI: (10.1016/j.cgh.2018.01.027) Copyright © 2018 AGA Institute Terms and Conditions

Figure 2 Forest plot showing study-specific and mean sensitivity and specificity of FE-1 compared with secretin stimulation test for exocrine pancreatic insufficiency with corresponding heterogeneity statistics. Clinical Gastroenterology and Hepatology 2018 16, 1220-1228.e4DOI: (10.1016/j.cgh.2018.01.027) Copyright © 2018 AGA Institute Terms and Conditions

Supplementary Figure 1 Scatter plot and chi-square plot for studies with secretin stimulation as gold standard. Clinical Gastroenterology and Hepatology 2018 16, 1220-1228.e4DOI: (10.1016/j.cgh.2018.01.027) Copyright © 2018 AGA Institute Terms and Conditions

Supplementary Figure 2 Deeks’ funnel plot for studies with secretin stimulation as gold standard. Clinical Gastroenterology and Hepatology 2018 16, 1220-1228.e4DOI: (10.1016/j.cgh.2018.01.027) Copyright © 2018 AGA Institute Terms and Conditions

Supplementary Figure 3 Deeks’ funnel plot for studies with quantitative fecal fat as gold standard. Clinical Gastroenterology and Hepatology 2018 16, 1220-1228.e4DOI: (10.1016/j.cgh.2018.01.027) Copyright © 2018 AGA Institute Terms and Conditions