Marc D. Silverstein, MDa,b, John W. Yunginger, MDc, Charles E

Slides:

Advertisements

Similar presentations

Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane- beclomethasone extrafine inhalation aerosol), in asthma Jennifer.

Advertisements

W.Travis Cain, MDa, Greg Cable, PhDb, John J. Oppenheimer, MDc

Incidence and Outcomes of Asthma in the Elderly

Double-blind placebo-controlled study of the efficacy of oral terfenadine in the treatment of chronic fatigue syndrome Paul Steinberg, MDa, Bruce E.

John A. Heit, MDa, Thom W. Rooke, MDa, Marc D

Diane J. Pincus, MD, Stanley J. Szefler, MD, Lynn M

Comparative efficacy and anti-inflammatory profile of once-daily therapy with leukotriene antagonist or low-dose inhaled corticosteroid in patients with.

Ann-Marie M. Schoos, MD, PhD, Jacob D

Wheat ω-5 gliadin is a major allergen in children with immediate allergy to ingested wheat Kati Palosuo, MDa,b, Elina Varjonen, MDa, Outi-Maria Kekki,

Practice Notes from the AAAI

Hydroxychloroquine improves airflow and lowers circulating IgE levels in subjects with moderate symptomatic asthma B.Lauren Charous, MD, Elkan F. Halpern,

Chronic sinusitis in severe asthma is related to sputum eosinophilia

Inflammation of small airways in asthma

Mark T. S. Chan, MDa, Donald Y. M. Leung, MD, PhDb, Stanley J

Elephantiasis nostras: A case report

Practice Notes from the AAAAI

Peter M. Wolfgram, MD, David B. Allen, MD

Side effects of inhaled corticosteroids

John A. Heit, MDa, Thom W. Rooke, MDa, Marc D

Anaphylactic reaction to local administration of rifamycin SV

Practice Notes from the AAAAI

Increased sensitivity to bradykinin among African Americans

A review of the current guidelines for allergic rhinitis and asthma

Physician-targeted program on inhaled therapy for childhood asthma

News & Notes Journal of Allergy and Clinical Immunology

James P. Kemp, MDa, David A. Cook, MDb, Gary A

Inflammatory cells, cytokine and chemokine expression in asthma immunocytochemistry and in situ hybridization Qutayba Hamid, MD, PhD, Editor Journal.

Interactions between breast-feeding, specific parental atopy, and sex on development of asthma and atopy Piush J. Mandhane, MD, Justina M. Greene, Dip.

Nasal provocation test with lysine-aspirin for diagnosis of aspirin-sensitive asthma Mamert Milewski, MD, Lucyna Mastalerz, MD, Ewa Niżankowska, MD, Andrzej.

Effect of ozone and nitrogen dioxide on the release of proinflammatory mediators from bronchial epithelial cells of nonatopic nonasthmatic subjects and.

IgE in unselected like-sexed monozygotic and dizygotic twins at birth and at 6 to 9 years of age: High but dissimilar genetic influence on IgE levels

Budesonide delivered by Turbuhaler is effective in a dose-dependent fashion when used in the treatment of adult patients with chronic asthma William.

Molecular virology and immunology of HIV infection

Jack M. Becker, MDa, Anjali Arora, MDb, Richard J

Clinical need for a nebulized corticosteroid

Pet-keeping in childhood and adult asthma and hay fever: European community respiratory health survey Cecilie Svanes, MD, PhDab, Joachim Heinrich, PhDc,

Vascular endothelial growth factor in patients with acute asthma

Autophagy: Nobel Prize 2016 and allergy and asthma research

A comparison of multiple doses of fluticasone propionate and beclomethasone dipropionate in subjects with persistent asthma Gordon D. Raphael, MDa, Robert.

News & Notes Journal of Allergy and Clinical Immunology

Low-dose inhaled fluticasone propionate versus oral zafirlukast in the treatment of persistent asthma Eugene R. Bleecker, MDa, Michael J. Welch, MDb,

Observations on emerging patterns of asthma in our society

Antiresorptive therapy in asthmatic patients receiving high-dose inhaled steroids: A prospective study for 18 months Wei Qing Wang, MB, Mary Sau Man.

The 30th anniversary of the American Board of Allergy and Immunology: Then and now Lynn Des Prez a, Charles E. Reed, MD, Lawrence B. Schwartz, MDb, John.

A prospective, controlled study showing that rubber gloves are the major contributor to latex aeroallergen levels in the operating room Dann K. Heilman,

Inhalation challenge testing of latex-sensitive health care workers and the effectiveness of laminar flow HEPA–filtered helmets in reducing rhinoconjunctival.

Preparing patients and health professionals for the transition to chlorofluorocarbon-free inhalers: The British perspective Helen Donohoe, MSc (Econ)

Practice Notes from the AAAI

Erika von Mutius, MD Journal of Allergy and Clinical Immunology

Normal pregnancy outcomes in a population-based study including 2968 pregnant women exposed to budesonide Ensio Norjavaara, MD, PhDa,b, Maria Gerhardsson.

Anaphylaxis after initial ingestion of rambutan, a tropical fruit

Determinants of systemic manifestations of food allergy

The allergy archives: Pioneers and Milestones

Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure Susan Colilla, PhDa*, Dan Nicolae, PhDb, Anna Pluzhnikov,

Abnormalities of cell and mediator levels in bronchoalveolar lavage fluid of patients with mild asthma Sally E. Wenzel, MD Journal of Allergy and Clinical.

Further studies on the chronotherapy of asthma with inhaled steroids: The effect of dosage timing on drug efficacy Diane J. Pincus, MD, Teresa R. Humeston,

Diane J. Pincus, MD, Stanley J. Szefler, MD, Lynn M

Reply Journal of Allergy and Clinical Immunology

Footnotes1 Journal of Allergy and Clinical Immunology

The Editors' Choice Journal of Allergy and Clinical Immunology

National trends in asthma visits and asthma pharmacotherapy,

Prescott G. Woodruff, MD, MPH, Ramin Khashayar, MD, Stephen C

Macrolide antibiotics and asthma treatment

Larry C. Borish, MDa, Harold S

Exhaled carbon monoxide levels after a course of oral prednisone in children with asthma exacerbation Stefania Zanconato, MD, PhD, Massimo Scollo, MD,

Budesonide Inhalation Suspension Versus Montelukast in Children Aged 2 to 4 Years with Mild Persistent Asthma Stanley J. Szefler, MD, Lars-Goran Carlsson,

Andrea J. Apter, MD, MSca, c, Susan T

The environmental predictors of allergic disease

Airway remodeling-associated mediators in moderate to severe asthma: Effect of steroids on TGF-β, IL-11, IL-17, and type I and type III collagen expression

News & Notes Journal of Allergy and Clinical Immunology

Presentation transcript:

Attained adult height after childhood asthma: Effect of glucocorticoid therapy Marc D. Silverstein, MDa,b, John W. Yunginger, MDc, Charles E. Reed, MDd, Tanya Petterson, MSb, Donald Zimmerman, MDc, James C. Li, MD, PhDd, W.Michael O'Fallon, PhDb Journal of Allergy and Clinical Immunology Volume 99, Issue 4, Pages 466-474 (April 1997) DOI: 10.1016/S0091-6749(97)70072-1 Copyright © 1997 Mosby, Inc. Terms and Conditions

Fig. 1 Adult height of men and women with asthma and age- and sex-matched nonasthmatic subjects by mid-parental height. Lines indicate the following equation: Adult height = 48.2 cm + (0.15 cm) × Asthma + (3.44 cm) × Male + (0.73 cm) × Mid-parental height, where Asthma = 1 if asthmatic, 0 if nonasthmatic; Male = 1 if male, 0 if female. Journal of Allergy and Clinical Immunology 1997 99, 466-474DOI: (10.1016/S0091-6749(97)70072-1) Copyright © 1997 Mosby, Inc. Terms and Conditions

Figure 2 Adult height of patients with asthma who received any glucocorticoid therapy during childhood or adolescence and patients with asthma who received no glucocorticoid therapy during childhood or adolescence by mid-parental height. Lines indicate the following equation: Adult height = 23.2 cm – (1.26 cm) × Glucocorticoid + (0.89 cm) × Mid-parental height, where Glucocorticoid = 1 if glucocorticoid recorded in medical recorded, 0 if no glucocorticoid therapy recorded in medical record. Journal of Allergy and Clinical Immunology 1997 99, 466-474DOI: (10.1016/S0091-6749(97)70072-1) Copyright © 1997 Mosby, Inc. Terms and Conditions

Figure 3 Adult height of patients with asthma who received oral or parenteral glucocorticoid therapy during childhood or adolescence, patients with asthma who received only inhaled glucocorticoids during childhood or adolescence, and patients with asthma who had no glucocorticoid exposure by mid-parental height. Lines indicated the following equation: Adult height = 23.0 cm – (1.40 cm) × Oral – (0.90 cm) × Inhaled + (0.89 cm) × Mid-parental height, where Oral = 1 if any glucocorticoid exposure, 0 if no exposure to oral glucocorticoids; and Inhaled = 1 if only inhaled glucocorticoid exposure, 0 if no exposure to any inhaled steroids. Journal of Allergy and Clinical Immunology 1997 99, 466-474DOI: (10.1016/S0091-6749(97)70072-1) Copyright © 1997 Mosby, Inc. Terms and Conditions

Figure 4 Difference between measured adult height of patients with asthma and mid-parental height versus logarithm of cumulative potency-adjusted glucocorticoid from onset of asthma to age of adult height (17 years for girls and 19 years for boys). Journal of Allergy and Clinical Immunology 1997 99, 466-474DOI: (10.1016/S0091-6749(97)70072-1) Copyright © 1997 Mosby, Inc. Terms and Conditions