Amoxicillin for acute lower-respiratory-tract infection in primary care when pneumonia is not suspected: a 12-country, randomised, placebo-controlled.

Slides:

Advertisements

Similar presentations

Crohn's disease Prof Daniel C Baumgart, MD, Prof William J Sandborn, MD The Lancet Volume 380, Issue 9853, Pages (November 2012) DOI: /S (12)

Advertisements

Optimisation of infection prevention and control in acute health care by use of behaviour change: a systematic review Rachel Edwards, MSc, Esmita Charani,

Volume 379, Issue 9824, Pages (April 2012)

Volume 364, Issue 9440, Pages (September 2004)

Volume 367, Issue 9517, Pages (April 2006)

Point-of-care C-reactive protein testing to reduce inappropriate use of antibiotics for non-severe acute respiratory infections in Vietnamese primary.

The Research Question Use of Antidepressants in Patients with Depression and Cardiometabolic Disease Bhautesh Jani, David Purves, Sarah Barry, Colin McCowan,

Year-round influenza immunisation during pregnancy in Nepal: a phase 4, randomised, placebo-controlled trial Prof Mark C Steinhoff, MD, Prof Joanne Katz,

Thank God for Richard Dawkins?

Paediatric HIV-1 infection

Intravenous or nebulised magnesium sulphate versus standard therapy for severe acute asthma (3Mg trial): a double-blind, randomised controlled trial

Volume 5, Issue 4, Pages (April 2006)

Development and internal validation of a clinical rule to improve antibiotic use in children presenting to primary care with acute respiratory tract infection.

Volume 355, Issue 9204, Pages (February 2000)

Point-of-care C-reactive protein testing to reduce inappropriate use of antibiotics for non-severe acute respiratory infections in Vietnamese primary.

Volume 389, Issue 10076, Pages (April 2017)

Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation.

Volume 371, Issue 9611, Pages (February 2008)

Effect of intravenous haloperidol on the duration of delirium and coma in critically ill patients (Hope-ICU): a randomised, double-blind, placebo-controlled.

An internet-based intervention with brief nurse support to manage obesity in primary care (POWeR+): a pragmatic, parallel-group, randomised controlled.

The Research Question The Reduction in ED and Hospital Admissions From Medical Home Practices is Specific to Primary-Care-Sensitive Chronic Conditions.

The Research Question Can a childhood obesity behavior modification program be implemented in primary care practices? Can participation in a childhood.

The Research Question Title: Current and future use of point-of-care test in primary care: an international survey in Australia, Belgium, the Netherlands,

The Research Question PCMH Transformation

Characteristics and survival of patients with Ebola virus infection, malaria, or both in Sierra Leone: a retrospective cohort study Matthew Waxman, MD,

The Research Question To examine which patient- and context-related factors impact the antidepressant efficacy of exercise in the real clinical world,

The Research Question Does longer duration of prescription opioid use lead to new onset depression when controlling for maximum daily dose, pain and other.

Volume 1, Issue 3, Pages (August 2014)

The Research Question Does Cardiovascular Risk Predict Statin Use?

Outcomes of a randomized trial for multimorbidity - the TrueBlue study

Volume 385, Issue 9966, Pages (January 2015)

Volume 392, Issue 10147, Pages (August 2018)

Trends in virological and clinical outcomes in individuals with HIV-1 infection and virological failure of drugs from three antiretroviral drug classes:

Volume 372, Issue 9642, Pages (September 2008)

Volume 2, Issue 6, Pages (June 2015)

Antibiotic prescription strategies for acute sore throat: a prospective observational cohort study Prof Paul Little, FMedSci, Beth Stuart, Prof F D Richard.

Volume 375, Issue 9732, Pages (June 2010)

Prevalence of tuberculosis, hepatitis C virus, and HIV in homeless people: a systematic review and meta-analysis Ulla Beijer, PhD, Achim Wolf, MSc, Dr.

Volume 385, Issue 9986, Pages (June 2015)

Volume 379, Issue 9812, Pages (January 2012)

Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double- blind, parallel-group, placebo-controlled trial Dr Andrew R Goudie,

M. Woodhead, F. Blasi, S. Ewig, J. Garau, G. Huchon, M. Ieven, A

Volume 382, Issue 9899, Pages (October 2013)

Volume 392, Issue 10158, Pages (November 2018)

Delayed antibiotic prescribing and associated antibiotic consumption in adults with acute cough by Nick A Francis, David Gillespie, Jacqueline Nuttall,

Intravenous or nebulised magnesium sulphate versus standard therapy for severe acute asthma (3Mg trial): a double-blind, randomised controlled trial

Volume 371, Issue 9627, Pages (May 2008)

Volume 378, Issue 9786, Pages (July 2011)

Volume 393, Issue 10172, Pages (February 2019)

Volume 5, Issue 4, Pages (April 2018)

Primary prophylaxis of cryptococcal disease with fluconazole in HIV-positive Ugandan adults: a double-blind, randomised, placebo-controlled trial Dr.

Thank God for Richard Dawkins?

Diagnosis of tuberculous meningitis with invasive pulmonary sampling

Physiotherapy breathing retraining for asthma: a randomised controlled trial Prof Anne Bruton, PhD, Prof Amanda Lee, PhD, Prof Lucy Yardley, PhD, Prof.

Effect of tobacco control policies on perinatal and child health: a systematic review and meta-analysis Timor Faber, MPH, Arun Kumar, MSc, Prof Johan.

Volume 375, Issue 9714, Pages (February 2010)

Volume 381, Issue 9878, Pages (May 2013)

Volume 11, Issue 3, Pages (March 2010)

Volume 392, Issue 10160, Pages (November 2018)

The Research Question Autoinflation as a treatment of Otitis Media with Effusion in primary care: a randomized controlled trial Williamson I, Vennik J,

Antibiotics for acute cough: an international observational study of patient adherence in primary care by Nick A Francis, David Gillespie, Jacqueline Nuttall,

Volume 14, Issue 9, Pages (August 2013)

Volume 372, Issue 9632, Pages (July 2008)

Influence of the duration of penicillin prescriptions on outcomes for acute sore throat in adults: the DESCARTE prospective cohort study in UK general.

The Research Question Clinical concern around iron deficiency anemia in young children centres on its association with poorer neurodevelopmental outcomes.

Cost effectiveness of amoxicillin for lower respiratory tract infections in primary care: an economic evaluation accounting for the cost of antimicrobial.

Volume 383, Issue 9930, Pages (May 2014)

Clinic attendance and disengagement of young adults with type 1 diabetes after transition of care from paediatric to adult services (TrACeD): a randomised,

Volume 371, Issue 9611, Pages (February 2008)

Symptom-based stratification of autoimmune diseases

Presentation transcript:

Amoxicillin for acute lower-respiratory-tract infection in primary care when pneumonia is not suspected: a 12-country, randomised, placebo-controlled trial Prof Paul Little, FRCGP, Beth Stuart, PhD, Michael Moore, FRCGP, Prof Samuel Coenen, DMSc, Prof Christopher C Butler, FRCGP, Prof Maciek Godycki-Cwirko, PhD, Prof Artur Mierzecki, PhD, Slawomir Chlabicz, PhD, Prof Antoni Torres, PhD, Jordi Almirall, MD, Mel Davies, MSc, Tom Schaberg, PhD, Prof Sigvard Mölstad, PhD, Prof Francesco Blasi, MD, An De Sutter, PhD, Prof Janko Kersnik, PhD, Helena Hupkova, PhD, Pia Touboul, MD, Prof Kerenza Hood, PhD, Mark Mullee, MSc, Gilly O'Reilly, PhD, Curt Brugman, MSc, Prof Herman Goossens, PhD, Prof Theo Verheij, PhD The Lancet Infectious Diseases Volume 13, Issue 2, Pages 123-129 (February 2013) DOI: 10.1016/S1473-3099(12)70300-6 Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 1 Trial profile The Lancet Infectious Diseases 2013 13, 123-129DOI: (10.1016/S1473-3099(12)70300-6) Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 2 Kaplan-Meier estimates for duration of symptoms rated “moderately bad” or worse The Lancet Infectious Diseases 2013 13, 123-129DOI: (10.1016/S1473-3099(12)70300-6) Copyright © 2013 Elsevier Ltd Terms and Conditions