Volume 15, Issue 10, Pages (September 2014)

Slides:

Advertisements

Similar presentations

Efficacy of neoadjuvant bevacizumab added to docetaxel followed by fluorouracil, epirubicin, and cyclophosphamide, for women with HER2-negative early breast.

Advertisements

Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials The Lancet Volume 386, Issue.

Aromatase inhibitors versus tamoxifen in early breast cancer: patient-level meta- analysis of the randomised trials The Lancet Volume 386, Issue 10001,

Volume 62, Issue 4, Pages (October 2012)

Volume 17, Issue 8, Pages (August 2016)

Volume 17, Issue 2, Pages (February 2016)

Volume 2, Issue 1, Pages (January 2015)

Volume 9, Issue 4, Pages (April 2008)

Volume 53, Issue 4, Pages (April 2008)

Volume 383, Issue 9920, Pages (March 2014)

Volume 72, Issue 5, Pages (November 2017)

Volume 17, Issue 2, Pages (February 2016)

Socioeconomic inequality in neonatal mortality in countries of low and middle income: a multicountry analysis Britt McKinnon, MSc, Sam Harper, PhD, Prof.

Depression and violence: a Swedish population study

Self-assessment of the outcome of early medical abortion versus clinic follow-up in India: a randomised, controlled, non-inferiority trial Dr Kirti Iyengar,

Effect of a lifestyle intervention on weight change in south Asian individuals in the UK at high risk of type 2 diabetes: a family-cluster randomised.

Banning of fetal sex determination and changes in sex ratio in India

Volume 15, Issue 10, Pages (September 2014)

Volume 9, Issue 5, Pages (May 2008)

Volume 3, Issue 5, Pages (May 2016)

Volume 16, Issue 8, Pages (August 2015)

Volume 387, Issue 10035, Pages (June 2016)

Volume 17, Issue 8, Pages (August 2016)

Volume 14, Issue 4, Pages (April 2015)

Volume 389, Issue 10065, Pages (January 2017)

Volume 53, Issue 4, Pages (April 2008)

The Good School Toolkit for reducing physical violence from school staff to primary school students: a cluster-randomised controlled trial in Uganda

The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials David Moher, MSc, Kenneth F Schulz,

Volume 3, Issue 2, Pages (February 2016)

Volume 15, Issue 2, Pages (February 2016)

Volume 17, Issue 2, Pages (February 2016)

Volume 15, Issue 4, Pages (April 2014)

Volume 9, Issue 10, Pages (October 2008)

Self-assessment of the outcome of early medical abortion versus clinic follow-up in India: a randomised, controlled, non-inferiority trial Dr Kirti Iyengar,

Mortality and its risk factors in Malawian children admitted to hospital with clinical pneumonia, 2001–12: a retrospective observational study Dr Marzia.

Volume 383, Issue 9920, Pages (March 2014)

Volume 2, Issue 1, Pages (January 2015)

Effect of nicotine patches in pregnancy on infant and maternal outcomes at 2 years: follow-up from the randomised, double-blind, placebo-controlled SNAP.

Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group,

Volume 71, Issue 3, Pages (March 2017)

Volume 386, Issue 9998, Pages (September 2015)

Volume 9, Issue 4, Pages (April 2008)

Lung cancer diagnosis and staging with endobronchial ultrasound-guided transbronchial needle aspiration compared with conventional approaches: an open-label,

Volume 387, Issue 10023, Pages (March 2016)

Effect of antenatal multiple micronutrient supplementation on anthropometry and blood pressure in mid-childhood in Nepal: follow-up of a double-blind.

Volume 72, Issue 5, Pages (November 2017)

Volume 13, Issue 1, Pages (January 2012)

Health consequences of exposure to e-waste: a systematic review

Socioeconomic inequality in neonatal mortality in countries of low and middle income: a multicountry analysis Britt McKinnon, MSc, Sam Harper, PhD, Prof.

Join us at The Lancet Clinic

Volume 389, Issue 10065, Pages (January 2017)

Volume 15, Issue 12, Pages (November 2014)

Prevalence of and factors associated with non-partner rape perpetration: findings from the UN Multi-country Cross-sectional Study on Men and Violence.

Volume 16, Issue 15, Pages (November 2015)

Volume 15, Issue 6, Pages (May 2014)

Volume 3, Issue 1, Pages (January 2016)

Volume 16, Issue 15, Pages (November 2015)

Volume 16, Issue 8, Pages (August 2015)

Volume 17, Issue 2, Pages (February 2016)

Volume 384, Issue 9957, Pages (November 2014)

Volume 386, Issue 10005, Pages (October 2015)

Volume 15, Issue 1, Pages (January 2014)

Metformin for non-diabetic patients with coronary heart disease (the CAMERA study): a randomised controlled trial Dr David Preiss, PhD, Suzanne M Lloyd,

Join us at The Lancet Clinic

Volume 2, Issue 4, Pages (April 2015)

Volume 387, Issue 10029, Pages (April 2016)

The effect of the Alive & Thrive initiative on exclusive breastfeeding in rural Burkina Faso: a repeated cross-sectional cluster randomised controlled.

Join us at The Lancet Clinic

Viral CNS infections in children from a malaria-endemic area of Malawi: a prospective cohort study Macpherson Mallewa, PhD, Prof Pam Vallely, PhD, Brian.

Volume 17, Issue 2, Pages (February 2016)

Presentation transcript:

Volume 15, Issue 10, Pages 1109-1118 (September 2014) Active monitoring, radical prostatectomy, or radiotherapy for localised prostate cancer: study design and diagnostic and baseline results of the ProtecT randomised phase 3 trial J Athene Lane, PhD, Prof Jenny L Donovan, PhD, Michael Davis, MSc, Eleanor Walsh, MSc, Daniel Dedman, MSc, Liz Down, BSc, Emma L Turner, PhD, Prof Malcolm D Mason, FRCP, Chris Metcalfe, PhD, Prof Tim J Peters, PhD, Richard M Martin, PhD, Prof David E Neal, FMedSci, Prof Freddie C Hamdy, FMedSci The Lancet Oncology Volume 15, Issue 10, Pages 1109-1118 (September 2014) DOI: 10.1016/S1470-2045(14)70361-4 Copyright © 2014 Lane et al. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 1 ProtecT and CAP trial recruitment phases and endpoint assessment CAP=Cluster randomised triAl of PSA testing for Prostate cancer. ProtecT=Prostate testing for cancer and Treatment. NHS=National Health Service. The Lancet Oncology 2014 15, 1109-1118DOI: (10.1016/S1470-2045(14)70361-4) Copyright © 2014 Lane et al. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 2 Flow diagram of the diagnostic phase of the main ProtecT trial Results are from one round of PSA testing. ASAP=atypical small acinar proliferation. PIN=prostatic intraepithelial neoplasia. PSA=prostate-specific antigen. The Lancet Oncology 2014 15, 1109-1118DOI: (10.1016/S1470-2045(14)70361-4) Copyright © 2014 Lane et al. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 3 Flow diagram of the randomisation phase of the ProtecT trial The Lancet Oncology 2014 15, 1109-1118DOI: (10.1016/S1470-2045(14)70361-4) Copyright © 2014 Lane et al. Open Access article distributed under the terms of CC BY Terms and Conditions