Fig. 1. miR-370 was downregulated, and GUCD1 was upregulated in HCC

Slides:



Advertisements
Similar presentations
Figure 1.1 The observer in the truck sees the ball move in a vertical path when thrown upward. (b) The Earth observer views the path of the ball as a parabola.
Advertisements

Suppl. Figure 1 A B Suppl. Figure 1. Relative (A) miR-21 and (B) miR-224 expression levels in HCC tumors in different stages (I,II,III,IV) assessed by.
Expression of Large Tenascin-C Splice Variants by Hepatic Stellate Cells in Chronic Hepatitis C Dr.Amro El-karef Assistant Professor of Pathology Department.
Supplementary Fig. 1. RT-PCR showed that tumor tissues have elevated Mst1 mRNA levels in most of the HCC patients tested. GAPDH RT-PCR products were shown.
INTRODUCTION & OBJECTIVES Introduction: The carcinogenesis of hepatocellular carcinoma (HCC) is a multifactorial, multistep and complex process. Its prognosis.
Podocalyxin-Like Protein 1 Expression and Correlation with Clinical Characteristics in Epithelial Serous and Mucinous Ovarian Carcinoma and Tumor-Like.
C/EBPα inhibits hepatocellular carcinoma by reducing Notch3/Hes1/p27 cascades  Yi-Chao Shi, Hong Zhao, Chuan Yin, Xin Zeng, Qing Zhang, Wen-Ping Xu, Ji.
Fig. 3. HNF1β and ERβ expressions in O-CCC. (A and B) HNF1β expression
Downregulation of MicroRNA-145 Caused by Hepatitis B Virus X Protein Promotes Expression of CUL5 and Contributes to Pathogenesis of Hepatitis B Virus-Associated.
MicroRNA-101 Inhibits Growth, Proliferation and Migration and Induces Apoptosis of Breast Cancer Cells by Targeting Sex-Determining Region Y-Box 2 Cell.
Fig. 3. Reverse transcription-PCR and Alkaline phosphatase staining assay. (A) ST2 cells were treated with Wnt7a, DKK1, and oligopeptide then the mRNA.
Figure S2 a b DBH-AS1 hDREH HBV-HCC HCV-HCC HDV-HCC HBV-HCC HCV-HCC
Effect of microRNA-135a on Cell Proliferation, Migration, Invasion, Apoptosis and Tumor Angiogenesis Through the IGF-1/PI3K/Akt Signaling Pathway in Non-Small.
Cell Physiol Biochem 2017;44:1867– DOI: /
Elevated FOXC2 Expression Promotes Invasion of HCC Cell Lines and is Associated with Poor Prognosis in Hepatocellular Carcinoma Cell Physiol Biochem 2017;44:99–109.
Cell Physiol Biochem 2016;40: DOI: /
Figure 1. Cellular distribution of a disintegrin and metalloproteinases (ADAM)-9 expression in hepatocellular carcinoma (HCC) and non-tumorous liver tissues.
Factor VII-Induced MicroRNA-135a Inhibits Autophagy and Is Associated with Poor Prognosis in Hepatocellular Carcinoma  Kuang-Tzu Huang, I-Ying Kuo, Ming-Chao.
Additional file 2 Total HCC cases N=39
KDM1B Expression in Richardson Breast 2
M. Fu, G. Huang, Z. Zhang, J. Liu, Z. Zhang, Z. Huang, B. Yu, F. Meng 
Upregulation of miR-142-3p Improves Drug Sensitivity of Acute Myelogenous Leukemia through Reducing P-Glycoprotein and Repressing Autophagy by Targeting.
Cell Physiol Biochem 2015;36: DOI: /
MicroRNA-489 Plays an Anti-Metastatic Role in Human Hepatocellular Carcinoma by Targeting Matrix Metalloproteinase-7  Yixiong Lin, Jianjun Liu, Yuqi Huang,
Volume 116, Issue 2, Pages (February 1999)
UHRF1 is regulated by miR-9 in colorectal cancer
Florie Borel, Pavlina Konstantinova, Peter L.M. Jansen 
MicroRNA-381 Represses ID1 and is Deregulated in Lung Adenocarcinoma
A microRNA profile comparison between thoracic aortic dissection and normal thoracic aorta indicates the potential role of microRNAs in contributing to.
Volume 19, Issue 2, Pages (February 2011)
Fig. 5. Stimulation of EPO expression and secretion under hypoxic culture conditions. Stimulation of EPO expression and secretion under hypoxic culture.
CHK1 downregulation upon ERG overexpression.
Microarray analysis of phospho-Twist1–responsive genes.
Fig. 7. Altering GUCD1 expression reversed the effect of miR-370 on cell EMT process in HCC. (A) Western blot and (B) qRT-PCR results showed that GUCD1overexpression.
Volume 54, Issue 5, Pages (May 2011)
Fig. 3. miR-370 overexpression suppressed cell migration and invasion in HCC cells. (A) miR-370 expression in miR-370 overexpressed HCCLM3 cells were detected.
Fig. 4. miR-370 restoration suppressed EMT progression in HCC cells
Correlation of mouse gene expression with bacterial gene expression.
Fig. 5. GUCD1 was a direct target of miR-370 in HCC
Fig. 6. Alteration of GUCD1 expression partially reversed the miR-370-mediated effect on HCC cell migration and invasion. (A) Western blot (up) and qRT-PCR.
mRNA level as % relative to
Bernard et al, Supplementary Figure S1
Fold Change of hsa-miR-3687 (T/N)(log2)
Promotion Effects of miR-375 on the Osteogenic Differentiation of Human Adipose- Derived Mesenchymal Stem Cells  Si Chen, Yunfei Zheng, Shan Zhang, Lingfei.
Molecular prognostication of liver cancer: End of the beginning
Non-invasive diagnosis and biomarkers in alcohol-related liver disease
Molecular Therapy - Nucleic Acids
Amplification and Overexpression of the EMS 1 Oncogene, a Possible Prognostic Marker, in Human Hepatocellular Carcinoma  Bao-Zhu Yuan, Xiaoling Zhou,
Volume 60, Issue 5, Pages (May 2014)
QRT-PCR analysis of the role of MDL-1 in expression of infection-regulated genes. qRT-PCR analysis was performed on infection-regulated genes that have.
MicroRNA-381 Represses ID1 and is Deregulated in Lung Adenocarcinoma
MiRNA Expression Profiling in Melanocytes and Melanoma Cell Lines Reveals miRNAs Associated with Formation and Progression of Malignant Melanoma  Daniel.
Increased expression levels of CHIT1 in the patients with IPF where they correlate inversely with SMAD7. Increased expression levels of CHIT1 in the patients.
Fig. 1. IL-31 and IL-31R mRNA expression was upregulated in the asthma mouse model. IL-31 and IL-31R mRNA expression was upregulated in the asthma mouse.
Fig. 3. Coilin levels correlate with altered nascent U2 snRNA, hTR and rRNA levels.RNA isolated from HeLa or WI-38 cells following RNAi targeting coilin.
Production of nerve growth factor by mouse hepatocellular carcinoma cells and expression of TrkA in tumor-associated arteries in mice  Kan Kishibe, Yoshihisa.
SIRT1 is downregulated in human gastric cancer (GC).
Supplemental Figure 1 Cell proliferation (% of mock)
Effects of Chd1-knockdown on Hmgpi and Klf5 expression
Chd1 expression and CHD1 localization during mouse preimplantation development. Chd1 expression and CHD1 localization during mouse preimplantation development.
Targeting eIF4E increases ZEB1 protein and mRNA levels and decreases ZEB1-targeting miR-200c and miR-141 microRNAs. Targeting eIF4E increases ZEB1 protein.
TFAP2A is highly expressed in nasopharyngeal carcinoma cells and tumor tissues. TFAP2A is highly expressed in nasopharyngeal carcinoma cells and tumor.
BORIS mRNA expression in DNMT deficient HCT116 cell lines.
Reduced klotho expression in pancreatic cancer.
Fig. 6 Antitumor effect on tumor growth and pulmonary metastasis of CSSD-9 in vivo. Antitumor effect on tumor growth and pulmonary metastasis of CSSD-9.
Tivantinib does not inhibit MET function.
Fig. 3. PTEN a target of miR-182-5p
lncRNA HOXA11-AS is overexpressed in gastric cancer tissues.
Introduction to Abbreviated Liver MRI Protocols
Fig. 1. FAM83H over-expression is associated with poor prognosis of CC
Presentation transcript:

Fig. 1. miR-370 was downregulated, and GUCD1 was upregulated in HCC Fig. 1. miR-370 was downregulated, and GUCD1 was upregulated in HCC. (A and B) miR-370 expression in HCC tissues and cells was measured using qRT-PCR. (C) GUCD1 expression in HCC and normal liver cells was detected by qRT-PCR. (D) Spearman's correlation analysis between the miR-370 expressions and GUCD1 mRNA expressions in HCC tissues.*p<0.05, †p<0.01. GUCD1, guanylylcyclase domain containing 1; HCC, hepatocellular carcinoma. Fig. 1. miR-370 was downregulated, and GUCD1 was upregulated in HCC. (A and B) miR-370 expression in HCC tissues and cells was measured using qRT-PCR. (C) GUCD1 expression in HCC and normal liver cells was detected by qRT-PCR. (D) Spearman's correlation analysis between the miR-370… Yonsei Med J. 2019 Mar;60(3):267-276. https://doi.org/10.3349/ymj.2019.60.3.267