Volume 38, Issue 5, Pages (May 2013)

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Presentation transcript:

Volume 38, Issue 5, Pages 1073-1079 (May 2013) Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis Simon Yona, Ki-Wook Kim, Yochai Wolf, Alexander Mildner, Diana Varol, Michal Breker, Dalit Strauss-Ayali, Sergey Viukov, Martin Guilliams, Alexander Misharin, David A. Hume, Harris Perlman, Bernard Malissen, Elazar Zelzer, Steffen Jung Immunity Volume 38, Issue 5, Pages 1073-1079 (May 2013) DOI: 10.1016/j.immuni.2013.05.008 Copyright © 2013 Elsevier Inc. Terms and Conditions

Figure 1 Reporter Gene Expression Profile of Macrophage Populations in Cx3cr1gfp/+, Cx3cr1cre/+:R26-yfp, and Tamoxifen-Treated Cx3cr1creER/+:R26-yfp Mice Immunity 2013 38, 1073-1079DOI: (10.1016/j.immuni.2013.05.008) Copyright © 2013 Elsevier Inc. Terms and Conditions

Figure 2 Dual Origins of Macrophages Immunity 2013 38, 1073-1079DOI: (10.1016/j.immuni.2013.05.008) Copyright © 2013 Elsevier Inc. Terms and Conditions

Figure 3 Reporter Gene Expression Profile of Mononuclear Phagocyte Precursors and Circulating Monocytes Immunity 2013 38, 1073-1079DOI: (10.1016/j.immuni.2013.05.008) Copyright © 2013 Elsevier Inc. Terms and Conditions

Figure 4 Monocyte Subset Dynamics Immunity 2013 38, 1073-1079DOI: (10.1016/j.immuni.2013.05.008) Copyright © 2013 Elsevier Inc. Terms and Conditions

Figure 5 Impaired BM Exit of Ly6C+ Blood Monocyte Affects the Ly6C– Cell Compartment Immunity 2013 38, 1073-1079DOI: (10.1016/j.immuni.2013.05.008) Copyright © 2013 Elsevier Inc. Terms and Conditions

Figure 6 Prevalence of Ly6C+ Blood Monocytes Determines the Circulation Half-Life of Ly6C– Blood Cells Immunity 2013 38, 1073-1079DOI: (10.1016/j.immuni.2013.05.008) Copyright © 2013 Elsevier Inc. Terms and Conditions