Altered amphiregulin expression induced by diverse luteinizing hormone receptor reactivity in granulosa cells affects IVF outcomes Ying Huang, Yue Zhao,

Slides:

Advertisements

Similar presentations

Chromosomal polymorphisms are associated with female infertility and adverse reproductive outcomes after infertility treatment: a 7-year retrospective.

Advertisements

Effect of androgen supplementation or modulation on ovarian stimulation outcome in poor responders: a meta-analysis Sesh Kamal Sunkara, Jyotsna Pundir,

Modified natural cycle IVF and mild IVF: a 10 year Swedish experience

Chromosomal polymorphisms are associated with female infertility and adverse reproductive outcomes after infertility treatment: a 7-year retrospective.

Kay Neumann, Georg Griesinger Reproductive BioMedicine Online

Volume 23, Issue 2, Pages (June 2016)

Blastocyst-stage versus cleavage-stage embryo transfer in women with high oestradiol concentrations: randomized controlled trial Eman A. Elgindy, Ahmed.

Live births after management of severe OHSS by GnRH antagonist administration in the luteal phase TG Lainas, IA Sfontouris, IZ Zorzovilis, GK Petsas,

Low-dosage clomiphene reduces premature ovulation rates and increases transfer rates in natural-cycle IVF M von Wolff, M Nitzschke, P Stute, N Bitterlich,

Live births achieved via IVF are increased by improvements in air quality and laboratory environment Ryan J. Heitmann, Micah J. Hill, Aidita N. James,

Effect of mid-follicular phase recombinant LH versus urinary HCG supplementation in poor ovarian responders undergoing IVF – a prospective double-blinded.

Luteinizing hormone/chorionic gonadotrophin receptor overexpressed in granulosa cells from polycystic ovary syndrome ovaries is functionally active Venkateswarlu.

Methodology matters: IVF versus ICSI and embryonic gene expression

Effect of HCG-day serum progesterone and oestradiol concentrations on pregnancy outcomes in GnRH agonist cycles Ze Wu, Rong Li, Yanping Ma, Bo Deng,

Bruce S. Shapiro, Said T. Daneshmand, Humberto Restrepo, Forest C

Higher β-HCG concentrations and higher birthweights ensue from single vitrified embryo transfers Kevin N. Keane, Kamarul Bahyah Mustafa, Peter Hinchliffe,

A. Osman, J. Pundir, M. Elsherbini, S. Dave, T. El-Toukhy, Y. Khalaf

Withdrawal of GnRH agonist decreases oestradiol and VEGF concentrations in high responders Li-Jun Ding, Bin Wang, Xiao-Yue Shen, Gui-Jun Yan, Ning-Yuan.

MiR-483–5p and miR-486–5p are down-regulated in cumulus cells of metaphase II oocytes from women with polycystic ovary syndrome Lin Shi, Shan Liu, Wanqiu.

Clinical utility of newly developed highly purified human menopausal gonadotrophins: a randomized controlled trial Hwa Seon Koo, Hwang Kwon, Doo Seok.

In vitro maturation improves oocyte or embryo cryopreservation outcome in breast cancer patients undergoing ovarian stimulation for fertility preservation

The effect of endometrial scratch on natural-cycle cryopreserved embryo transfer outcomes: a randomized controlled study Jennifer Sze Man Mak, Cathy.

Circulating concentration of stem cell factor in serum of stimulated IVF patients Ali Salmassi, Sandy Zorn, Liselotte Mettler, Kerstin Koch, Walter Jonat,

Factors affecting embryo viability and uterine receptivity: insights from an analysis of the UK registry data Stephen A. Roberts, Mark Hann, Daniel R.

Anti-Müllerian hormone as a predictor of pregnancy following IVF

Tanja Burnik Papler, Eda Vrtačnik Bokal, Aleš Maver, Luca Lovrečić

Inositol supplementation in women with polycystic ovary syndrome undergoing intracytoplasmic sperm injection: a systematic review and meta-analysis of.

Impact of high serum progesterone during the late follicular phase on IVF outcome Charlotte Sonigo, Géraldine Dray, Clémence Roche, Isabelle Cédrin-Durnerin,

Perinatal outcomes after stimulated versus natural cycle IVF: a systematic review and meta-analysis Mohan Shashikant Kamath, Richard Kirubakaran, Mariano.

Systematic review of the clinical efficacy of vaginal progesterone for luteal phase support in assisted reproductive technology cycles Tim Child, Saoirse.

The effect of a high progesterone concentration before oocyte retrieval on the peri- implantation endometrium Liu Liu, Sumaia Sailan, Tinchiu Li, Najat.

Expression of growth differentiation factor-9 and bone morphogenetic protein-15 in oocytes and cumulus granulosa cells of patients with polycystic ovary.

Does supplementation of in-vitro culture medium with melatonin improve IVF outcome in PCOS? Mi Kyoung Kim, Eun A. Park, Hyung Joon Kim, Won Yun Choi,

Maternal concentrations of human chorionic gonadotrophin in very early IVF pregnancies and duration of pregnancy: a follow-up study Tom G. Tanbo, Manuela.

Prognostic factors influencing fresh and frozen IVF outcomes: an analysis of the UK national database W. Mark Hirst, Andy Vail, Daniel R. Brison, Stephen.

Individual demands of human embryos on IVF culture medium: influence on blastocyst development and pregnancy outcome B. Wirleitner, P. Vanderzwalmen,

M. Dieterich, M. Bolz, T. Reimer, S. Costagliola, B. Gerber

Impact of ovarian endometrioma on ovarian responsiveness and IVF: a systematic review and meta-analysis Chun Yang, Yuhong Geng, Yanhui Li, Chunyan Chen,

Randomized, controlled, open-label, non-inferiority study of the CONSORT algorithm for individualized dosing of follitropin alfa F. Olivennes, G. Trew,

Anti-Müllerian hormone for prediction of ovarian response in Chinese infertile women undergoing IVF/ICSI cycles: a prospective, multi-centre, observational.

The codon 72 polymorphism of the TP53 gene and endometriosis risk: a meta-analysis Yi Feng, Yuan-Yuan Wu, Li Li, Zhi-Juan Luo, Zhong Lin, Ying-Hui Zhou,

Sequential use of letrozole and gonadotrophin in women with poor ovarian reserve: a randomized controlled trial Vivian Chi Yan Lee, Carina Chi Wai Chan,

Lisa Cummins, Juliette Koch, Suha Kilani

Spontaneous ovulation versus HCG triggering for timing natural-cycle frozen–thawed embryo transfer: a randomized study Ariel Weissman, Eran Horowitz,

Ronit Machtinger, Raoul Orvieto Reproductive BioMedicine Online

Dehydroepiandrostendione sulphate and prediction of live birth after IVF in young women with low anti-Müllerian hormone concentration Miro Šimun Alebić,

Effect of chromosomal polymorphisms of different genders on fertilization rate of fresh IVF–ICSI embryo transfer cycles Ji Liang, Yongsheng Zhang, Yang.

Michael J. Levy, William Ledger, Efstratios M. Kolibianakis, Pieta C

Discrimination and characterization of Sertoli cell-only syndrome in non-obstructive azoospermia using cell-free seminal DDX4 Qiong Yu, Xiuli Gu, Xuejun.

The changing pattern of uterine contractions before and after fresh embryo transfer and its relation to clinical outcome Cathy Hoi Sze Chung, Alice Wai.

Stanley Paul Leibo (1937–2014): scientist, mentor and friend

Elevation of antimüllerian hormone in women with polycystic ovary syndrome undergoing assisted reproduction: effect of insulin Xing Yan Liu, M.Sc., Yun.

Does ovarian stimulation regimen affect IVF outcome

Follicle recruitment determines IVF productivity rate via the number of embryos frozen and subsequent transfers James D. Stanger, John L. Yovich Reproductive.

Anna Pia Ferraretti, Paul Devroey, M. Cristina Magli, Luca Gianaroli

Pietro Gambadauro, Ramesan Navaratnarajah

Effect of repeated cryopreservation on human embryo developmental potential Xiaoying Zheng, Yuan Chen, Jie Yan, Yuqi Wu, Xinjie Zhuang, Shengli Lin, Jinliang.

Samuel Kofi Arhin, Yu Zhao, XiaoSheng Lu, Mandika Chetry, JieQiang Lu

Genome-wide analysis shows no genomic predictors of ovarian response to stimulation by exogenous FSH for IVF Jeroen van Disseldorp, Lude Franke, Rene.

Cryopreserved embryo transfer: adjacent or non-adjacent to failed fresh long GnRH- agonist protocol IVF cycle Alexander Volodarsky-Perel, Talia Eldar-Geva,

Anti-Müllerian hormone is highly expressed and secreted from cumulus granulosa cells of stimulated preovulatory immature and atretic oocytes Alon Kedem-Dickman,

Effect of piroxicam administration before embryo transfer on IVF outcome: a randomized controlled trial Luca Dal Prato, Andrea Borini Reproductive BioMedicine.

Jing Zhao, Qiong Zhang, Yonggang Wang, Yanping Li

Progesterone elevation on the day of HCG administration may affect rescue ICSI Bo Huang, Zhou Li, Lixia Zhu, Dan Hu, Qun Liu, Guijin Zhu, Hanwang Zhang

Depression and state anxiety scores during assisted reproductive treatment are associated with outcome: a meta-analysis Satvinder Purewal, Sarah C.E.

Efficacy and safety of human chorionic gonadotropin for follicular phase stimulation in assisted reproduction: a systematic review and meta-analysis

John Yovich, James Stanger, Peter Hinchliffe

Fast action of estrogen on intracellular calcium in dormant mouse blastocyst and its possible mechanism Lin-lin Yu, M.Sc., Jin-hu Zhang, M.B., Ya-ping.

Use of progestins to inhibit spontaneous ovulation during ovarian stimulation: the beginning of a new era? Antonio La Marca, Martina Capuzzo Reproductive.

High oestradiol concentration after ovarian stimulation is associated with lower maternal serum beta-HCG concentration and neonatal birth weight Suying.

Presentation transcript:

Altered amphiregulin expression induced by diverse luteinizing hormone receptor reactivity in granulosa cells affects IVF outcomes Ying Huang, Yue Zhao, Yang Yu, Rong Li, Shengli Lin, Chunmei Zhang, Ping Liu, Jie Qiao Reproductive BioMedicine Online Volume 30, Issue 6, Pages 593-601 (June 2015) DOI: 10.1016/j.rbmo.2015.03.001 Copyright © 2015 Terms and Conditions

Figure 1 Correlation between the amphiregulin (AREG) mRNA level in mural granulosa cells and IVF outcomes. (A) AREG expression level is positively correlated with the number of oocytes retrieved; (B) metaphase II oocytes; and (C) good-quality embryos. Reproductive BioMedicine Online 2015 30, 593-601DOI: (10.1016/j.rbmo.2015.03.001) Copyright © 2015 Terms and Conditions

Figure 2 Correlation between the amphiregulin (AREG) mRNA level in cumulus granulosa cells and IVF outcomes. The level of AREG expression is positively correlated with (A) the number of oocytes retrieved; (B) metaphase II oocytes; (C) two pronuclei zygotes; and (D) good-quality embryos. Reproductive BioMedicine Online 2015 30, 593-601DOI: (10.1016/j.rbmo.2015.03.001) Copyright © 2015 Terms and Conditions

Figure 3 Amphiregulin (AREG) and epiregulin (EREG) expression changes in mural granulosa cells after human chorionic gonadotrophin (HCG) stimulation. (A) mRNA expression level of AREG and EREG in mural granulosa cells followed by HCG at the indicated times. The data were shown as fold-change compared with the control (0 h) (mean ± SD); (B) comparison of fold-changes of AREG and EREG expression at 4 h after the HCG stimulation between the pregnant and non-pregnant groups (mean ± SD) (*P < 0.05 versus the non-pregnant group); (C) the increase of AREG expression at 4 h after stimulation was positively correlated with the number of good quality embryos (P < 0.05). Reproductive BioMedicine Online 2015 30, 593-601DOI: (10.1016/j.rbmo.2015.03.001) Copyright © 2015 Terms and Conditions