Osteoarthritis and Cartilage

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In This Issue Cell Volume 145, Issue 3, (April 2011)

General Information Osteoarthritis and Cartilage

Presentation transcript:

Osteoarthritis and Cartilage Automatic 3D Selection, Segmentation, and Analysis of Human Articular Cartilage Chondrons from Micro-computed Tomography in vitro I. Kestilä, J.P. Thevenot, M.A. Finnilä, S.S. Karhula, I. Hadjab, S. Kauppinen, M. Garon, E. Quenneville, L. Rieppo, K.P. Pritzker, M.D. Buschmann, H.J. Nieminen, S. Saarakkala Osteoarthritis and Cartilage Volume 25, (April 2017) DOI: 10.1016/j.joca.2017.02.538 Copyright © 2017 Terms and Conditions

Figure 1. Top row: The average chondron volumes grouped by the OARSI histological grades (0–1.0 & 3.0–3.5) in three AC zones (0–10%, 10–40%, 40–100% from the AC surface). All the well segmented chondrons, chondrons containing a single cell, and chondrons containing a cluster were studied separately. *: p value 0.01 to 0.05, **: p value 0.001 to 0.01. Bottom row: Left; A–D: Example images of three orthogonal views from the manual segmentation verification. A = a well segmented cluster, B = a poorly segmented cluster, C = a well segmented single cell, D = a poorly segmented single cell. Right; 3D models of the segmented chondrons from representative OARSI 0 and OARSI 3 samples. Osteoarthritis and Cartilage 2017 25, DOI: (10.1016/j.joca.2017.02.538) Copyright © 2017 Terms and Conditions