Maternal microchimerism protects against the development of asthma

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Presentation transcript:

Maternal microchimerism protects against the development of asthma Emma E. Thompson, PhD, Rachel A. Myers, PhD, Gaixin Du, MS, Tessa M. Aydelotte, BA, Christopher J. Tisler, MS, Debra A. Stern, MS, Michael D. Evans, MS, Penelope E. Graves, ScD, Daniel J. Jackson, MD, Fernando D. Martinez, MD, James E. Gern, MD, Anne L. Wright, PhD, Robert F. Lemanske, MD, Carole Ober, PhD Journal of Allergy and Clinical Immunology Volume 132, Issue 1, Pages 39-44.e4 (July 2013) DOI: 10.1016/j.jaci.2012.12.1575 Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Forest plot showing the ORs and 95% CIs for asthma risk among MMc-positive subjects. The box sizes are proportional to the sample sizes. Journal of Allergy and Clinical Immunology 2013 132, 39-44.e4DOI: (10.1016/j.jaci.2012.12.1575) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 MMc rates by birth order (A) and age (B) in the COAST cohort (N = 107), the Tucson IIS cohort (N = 107), and the Hutterites (N = 103). Numbers of subjects are listed on the x axis for each category, and the proportion of MMc-positive subjects is shown on the y axis. Journal of Allergy and Clinical Immunology 2013 132, 39-44.e4DOI: (10.1016/j.jaci.2012.12.1575) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions