A Single Institution-Based Retrospective Study of Surgically Treated Bronchioloalveolar Adenocarcinoma of the Lung: Clinicopathologic Analysis, Molecular.

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A Single Institution-Based Retrospective Study of Surgically Treated Bronchioloalveolar Adenocarcinoma of the Lung: Clinicopathologic Analysis, Molecular Features, and Possible Pitfalls in Routine Practice Christian Casali, MD, Giulio Rossi, MD, Alessandro Marchioni, MD, Giuliana Sartori, PhD, Federica Maselli, MD, Lucia Longo, MD, Emilia Tallarico, MD, Uliano Morandi, MD Journal of Thoracic Oncology Volume 5, Issue 6, Pages 830-836 (June 2010) DOI: 10.1097/JTO.0b013e3181d60ff5 Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Example of a nonmucinous BAC (A, hematoxylin and eosin; original magnification, ×155), mucinous BAC (B, hematoxylin and eosin; original magnification, ×100), mixed BAC (C, hematoxylin and eosin; original magnification, ×155). Positive immunostaining for EGFR in a nonmucinous BAC (D, EGFR, immunohistochemistry, magnification ×155), and HER2/neu in a mucinous BAC (E, HER2/neu, immunohistochemistry, magnification ×100). Journal of Thoracic Oncology 2010 5, 830-836DOI: (10.1097/JTO.0b013e3181d60ff5) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Kaplan-Meier survival curves. A, Overall survival for clinical pattern (p = 0.048); B, Overall survival for BAC histologic subtype (p = 0.021); C, Overall survival for pathologic stage (p = 0.006); D, Solitary early stages (stages IA and IB; p = 0.044). Journal of Thoracic Oncology 2010 5, 830-836DOI: (10.1097/JTO.0b013e3181d60ff5) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions