Five-minute parameter of thromboelastometry is sufficient to detect thrombocytopenia and hypofibrinogenaemia in patients undergoing liver transplantation 

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Five-minute parameter of thromboelastometry is sufficient to detect thrombocytopenia and hypofibrinogenaemia in patients undergoing liver transplantation  J.-G. Song, S.-M. Jeong, I.-G. Jun, H.-M. Lee, G.-S. Hwang  British Journal of Anaesthesia  Volume 112, Issue 2, Pages 290-297 (February 2014) DOI: 10.1093/bja/aet325 Copyright © 2014 The Author(s) Terms and Conditions

Fig 1 Correlations between early ROTEM parameters and MCF. Early ROTEM parameters (A5 and A10) on all ROTEM assays (EXTEM, INTEM, and FIBTEM) demonstrated excellent correlations with MCF. British Journal of Anaesthesia 2014 112, 290-297DOI: (10.1093/bja/aet325) Copyright © 2014 The Author(s) Terms and Conditions

Fig 2 Intraoperative trends of ROTEM and laboratory parameters. Data are median (sd). T0, 1 h after induction of general anaesthesia; T1, 1 h after surgical incision; T2, 30 min after hepatectomy; T3, 30 min after graft reperfusion; T4, after hepatic artery anastomosis. British Journal of Anaesthesia 2014 112, 290-297DOI: (10.1093/bja/aet325) Copyright © 2014 The Author(s) Terms and Conditions

Fig 3 Linear (r) and curvilinear (R2) relationship between ROTEM parameters and conventional coagulation tests. Note that A5, A10, and MCF on both EXTEM and INTEM showed good correlations with PLTs and moderate correlations with fibrinogen concentration. A5, A10, and MCF of FIBTEM also showed good correlations with fibrinogen concentration. British Journal of Anaesthesia 2014 112, 290-297DOI: (10.1093/bja/aet325) Copyright © 2014 The Author(s) Terms and Conditions

Fig 4 ROC curves of A5 and A10 on EXTEM, INTEM, and FIBTEM predicting thrombocytopenia and hypofibrinogenaemia. AUC values of A5 and A10 on both EXTEM and INTEM were good predictors of PLTs <30×103 and <50×103 mm−3. AUC values of A5, A10, and MCF on FIBTEM were good predictors of fibrinogen <100 mg dl−1. British Journal of Anaesthesia 2014 112, 290-297DOI: (10.1093/bja/aet325) Copyright © 2014 The Author(s) Terms and Conditions