Volume 14, Issue 4, Pages (April 2017)

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Presentation transcript:

Volume 14, Issue 4, Pages 541-547 (April 2017) Device pacing diagnostics overestimate effective cardiac resynchronization therapy pacing results of the hOLter for Efficacy analysis of CRT (OLÉ CRT) study  Antonio Hernández‐Madrid, MD, Domenico Facchin, MD, Ruth Nicholson Klepfer, PhD, Subham Ghosh, PhD, Roberto Matía, MD, Javier Moreno, MD, Alessandro Locatelli, MD  Heart Rhythm  Volume 14, Issue 4, Pages 541-547 (April 2017) DOI: 10.1016/j.hrthm.2017.01.022 Copyright © 2017 The Authors Terms and Conditions

Figure 1 Unipolar electrogram highlighting the relevant features of the morphology when evaluating effective capture of the left ventricular pace. All parameters are evaluated from after the ventricular pace to 170 ms later. BL = baseline; Max = peak positive amplitude; Min = peak negative amplitude; Tmax = time when Max occurred; Tmin = time when Min occurred. Heart Rhythm 2017 14, 541-547DOI: (10.1016/j.hrthm.2017.01.022) Copyright © 2017 The Authors Terms and Conditions

Figure 2 Each bar represents an individual subject in the study. Colors represent the time spent in effective CRT (blue), ineffective CRT (green), and sensing (red). Subjects are ordered in increasing amounts of effective CRT. CRT = cardiac resynchronization therapy. Heart Rhythm 2017 14, 541-547DOI: (10.1016/j.hrthm.2017.01.022) Copyright © 2017 The Authors Terms and Conditions

Figure 3 Percent effective CRT pacing vs %V pacing for each subject. Dashed line is the line of identity. CRT = cardiac resynchronization therapy; V = ventricular. Heart Rhythm 2017 14, 541-547DOI: (10.1016/j.hrthm.2017.01.022) Copyright © 2017 The Authors Terms and Conditions

Figure 4 Example electrogram from a patient with atrial fibrillation (B021). Ineffective paced beats are highlighted with red circles. The label below each ventricular event is the device marker: BV = biventricular pace; VS = ventricular sense. Heart Rhythm 2017 14, 541-547DOI: (10.1016/j.hrthm.2017.01.022) Copyright © 2017 The Authors Terms and Conditions

Figure 5 Examples of ineffective and effective pacing in a subject with LV latency (A002). A: Baseline electrogram morphology looks like complete loss of capture. B: When the LV is preexcited enough, there is an initial negative deflection, and effective capture can be seen. BiV = biventricular; LV = left ventricle. Heart Rhythm 2017 14, 541-547DOI: (10.1016/j.hrthm.2017.01.022) Copyright © 2017 The Authors Terms and Conditions