Allosteric site of B. subtilis PRPP synthase.

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Allosteric site of B. subtilis PRPP synthase. Allosteric site of B. subtilis PRPP synthase. Stereo view based on the mADP PRPP synthase structure (PDB code 1dku) (49). The site is occupied by methylene ADP. Amino acid residues contributing to methylene ADP binding are provide by three subunits, labeled A, B, and D, as in Fig. 3. Amino acid residues of subunit A are shown in blue, amino acid residues of subunit B are in light gray, and amino acid residues of subunit D are shown in dark gray. Bjarne Hove-Jensen et al. Microbiol. Mol. Biol. Rev. 2017; doi:10.1128/MMBR.00040-16