The Ratio of the Maximum High Attenuation Area Dimension to the Maximum Tumor Dimension May Be an Index of the Presence of Lymph Node Metastasis in Lung.

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Presentation transcript:

The Ratio of the Maximum High Attenuation Area Dimension to the Maximum Tumor Dimension May Be an Index of the Presence of Lymph Node Metastasis in Lung Adenocarcinomas 3 cm or Smaller on High-Resolution Computed Tomography  Ryota Nishio, MD, Soichi Akata, Kazuhiro Saito, Tatsuo Ohira, Masahiro Tsuboi, Takashi Hirano, Norihiko Ikeda, Fumio Kotake, Harubumi Kato, Kimihiko Abe  Journal of Thoracic Oncology  Volume 2, Issue 1, Pages 29-33 (January 2007) DOI: 10.1016/S1556-0864(15)30014-9 Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Measurement of tumor dimension and high-attenuation area. H/T ratio, ratio of the maximum dimension of the intratumor high-attenuation area (H) to the maximum dimension of the tumor (T). Journal of Thoracic Oncology 2007 2, 29-33DOI: (10.1016/S1556-0864(15)30014-9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Case 1. True negative: An 81-year-old woman. High-resolution computed tomography scan of the right upper lobe shows a nodule with a maximum dimension of 19 mm with no high-attenuation area (H/T ratio = 0%). The absence of lymph node metastasis (N0) was confirmed pathologically. H/T ratio, ratio of the maximum dimension of the intratumor high- attenuation area (H) to the maximum dimension of the tumor (T). Journal of Thoracic Oncology 2007 2, 29-33DOI: (10.1016/S1556-0864(15)30014-9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Case 2. True negative: A 73-year-old woman. High-resolution computed tomography scan of the right upper lobe shows a nodule with a maximum dimension of 26 mm and a 15-mm high-attenuation area (H/T ratio = 57.6%). The absence of lymph node metastasis (N0) was confirmed pathologically. H/T ratio, ratio of the maximum dimension of the intratumor high-attenuation area (H) to the maximum dimension of the tumor (T). Journal of Thoracic Oncology 2007 2, 29-33DOI: (10.1016/S1556-0864(15)30014-9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 4 Case 3. True positive: A 62-year-old man. High-resolution computed tomography scan of the left upper lobe shows a nodule with a maximum dimension of 16 mm and a 15-mm high-attenuation area (H/T ratio = 93.8%). Ipsilateral hilar lymph node metastases (N1) were confirmed pathologically. H/T ratio, ratio of the maximum dimension of the intratumor high-attenuation area (H) to the maximum dimension of the tumor (T). Journal of Thoracic Oncology 2007 2, 29-33DOI: (10.1016/S1556-0864(15)30014-9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 5 Case 4. False positive: A 52-year-old man. High-resolution computed tomography scan of the right upper lobe shows a nodule with a maximum dimension of 24 mm and a 17-mm high-attenuation area (H/T ratio = 70.3%). The H/T ratio exceeded 60%, but there was no lymph node metastasis (N0). H/T ratio, ratio of the maximum dimension of the intratumor high-attenuation area (H) to the maximum dimension of the tumor (T). Journal of Thoracic Oncology 2007 2, 29-33DOI: (10.1016/S1556-0864(15)30014-9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 6 Case 5. True positive: A 71-year-old man. High-resolution computed tomography scan of the right upper lobe shows a nodule with a maximum dimension of 6 mm and a 6-mm high-attenuation area (H/T ratio = 100%). Even though it was a small tumor of only 6 mm, ipsilateral hilar lymph node metastasis metastases (N1) were confirmed pathologically. H/T ratio, ratio of the maximum dimension of the intratumor high-attenuation area (H) to the maximum dimension of the tumor (T). Journal of Thoracic Oncology 2007 2, 29-33DOI: (10.1016/S1556-0864(15)30014-9) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions