Should we continue to measure endometrial thickness in modern-day medicine? The effect on live birth rates and birth weight Vânia Costa Ribeiro, Samuel.

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Presentation transcript:

Should we continue to measure endometrial thickness in modern-day medicine? The effect on live birth rates and birth weight Vânia Costa Ribeiro, Samuel Santos-Ribeiro, Neelke De Munck, Panagiotis Drakopoulos, Nikolaos P. Polyzos, Valerie Schutyser, Greta Verheyen, Herman Tournaye, Christophe Blockeel Reproductive BioMedicine Online Volume 36, Issue 4, Pages 416-426 (April 2018) DOI: 10.1016/j.rbmo.2017.12.016 Copyright © 2018 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 Predicted endometrial thickness (EMT) according to (A) the duration of ovarian stimulation and (B) late-follicular oestradiol. The figure depicts the predicted mean EMT (teal line) and 95% CI (teal area); The full regression model is detailed in Supplementary Table S1. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.) Reproductive BioMedicine Online 2018 36, 416-426DOI: (10.1016/j.rbmo.2017.12.016) Copyright © 2018 Reproductive Healthcare Ltd. Terms and Conditions

Figure 2 Predicted live birth rates according to endometrial thickness. The figure depicts the predicted live birth rates after multivariable regression analysis adding endometrial thickness (EMT) as either a continuous (model 1, teal solid line and area for predicted liv birth rate and 95% CI) or categorical-ordinal (model 2, blue dashed line) variable; the full regression models are detailed in Supplementary Table S2. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.) Reproductive BioMedicine Online 2018 36, 416-426DOI: (10.1016/j.rbmo.2017.12.016) Copyright © 2018 Reproductive Healthcare Ltd. Terms and Conditions

Figure 3 Surface plots of the relationship between the effects of (A) endometrial thickness (EMT) and late-follicular oestradiol and (B) progesterone on live birth. Predicted live birth probabilities derived from the regression model detailed in Supplementary Table S2 (model 1). Reproductive BioMedicine Online 2018 36, 416-426DOI: (10.1016/j.rbmo.2017.12.016) Copyright © 2018 Reproductive Healthcare Ltd. Terms and Conditions

Figure 4 Predicted birth weight z-scores according to endometrial thickness. The figure depicts the predicted birth weight z-scores after multivariable generalized estimating equation regression adding endometrial thickness (EMT) as either a continuous (model 1, teal solid line and area for predicted z-score and 95% CI) or categorical-ordinal (model 2, blue dashed line) variable; the regression models are described in Table 3. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.) Reproductive BioMedicine Online 2018 36, 416-426DOI: (10.1016/j.rbmo.2017.12.016) Copyright © 2018 Reproductive Healthcare Ltd. Terms and Conditions