Acute generalized exanthematous pustulosis induced by mifepristone

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Acute generalized exanthematous pustulosis induced by mifepristone Brandon M. Kirsch, MD, Mark A. Cappel, MD JAAD Case Reports Volume 1, Issue 4, Pages 191-195 (July 2015) DOI: 10.1016/j.jdcr.2015.04.001 Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 AGEP. Diffuse erythematous eruption covered with several hundred superficial, nonfollicular pustules. Patient reported burning of the skin. Note confluence of pustules into lakes of pus. JAAD Case Reports 2015 1, 191-195DOI: (10.1016/j.jdcr.2015.04.001) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Accentuation in the skin folds including the waistline, intergluteal cleft, and popliteal fossae. JAAD Case Reports 2015 1, 191-195DOI: (10.1016/j.jdcr.2015.04.001) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Biopsy specimens reveal typical histologic features of acute generalized exanthematous pustulosis. Note subcorneal pustules with neutrophils and perivascular mixed inflammatory infiltrate. (Hematoxylin-eosin stain; original magnifications: ×4 [top], ×10 [middle], ×20 [bottom].) JAAD Case Reports 2015 1, 191-195DOI: (10.1016/j.jdcr.2015.04.001) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 4 Brisk perivascular infiltrate with many eosinophils and focal small-vessel vasculitis. (Hematoxylin-eosin stain; original magnifications: ×20 [top], ×40 [bottom].) JAAD Case Reports 2015 1, 191-195DOI: (10.1016/j.jdcr.2015.04.001) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions