On the Tip of the Tongue Neuron

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On the Tip of the Tongue Neuron Anat Maril, Anthony D. Wagner, Daniel L. Schacter  Neuron  Volume 31, Issue 4, Pages 653-660 (August 2001) DOI: 10.1016/S0896-6273(01)00396-8

Figure 1 Four Regions Demonstrated a TOT-Selective Response Displayed are axial sections through each region that demonstrated a TOT-selective response and averaged event-related responses associated with each retrieval outcome. Activation was significantly above baseline only during the TOT state in right middle frontal cortex (BA 9; 30, 51, 27), anterior cingulate cortex (BA 32/24; −6, 39, 21), right middle temporal cortex (BA 21; 51, −24, −12), and right inferior frontal cortex (BA 44/45; 51, 15, −3). DK, don't know; K, know; TOT, tip of the tongue Neuron 2001 31, 653-660DOI: (10.1016/S0896-6273(01)00396-8)

Figure 2 Averaged Event-Related Responses in TOT-Selective Regions, with Know and Don't Know Trials Median Split by RT For all regions, a greater response was observed during TOT trials relative to the long and the short response latency know and don't know trials. DK-L, long don't know; DK-S, short don't know; K-L, long know; K-S, short know; TOT, tip of the tongue Neuron 2001 31, 653-660DOI: (10.1016/S0896-6273(01)00396-8)

Figure 3 Effects of Retrieval Effort and Retrieval Success Were Observed in Frontal and Inferior Temporal Cortices Displayed are functionally defined ROIs and the resultant averaged event-related responses. The extent of activation in left inferior/middle frontal (BA 46/9; −42, 12, 31) and left inferior frontal (BA 44/45; −48, 18, 0) cortices covaried with retrieval effort, as indexed by RT. In contrast, left occipito-temporal cortex (BA 37/19; −51, −51, −24) demonstrated greater activation during trials accompanied by successful knowledge recovery Neuron 2001 31, 653-660DOI: (10.1016/S0896-6273(01)00396-8)