Lucas Goense, MD, Peter S. N. van Rossum, MD, Jelle P

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Presentation transcript:

Radiation to the Gastric Fundus Increases the Risk of Anastomotic Leakage After Esophagectomy Lucas Goense, MD, Peter S.N. van Rossum, MD, Jelle P. Ruurda, MD, PhD, Marco van Vulpen, MD, PhD, Stella Mook, MD, PhD, Gert J. Meijer, PhD, Richard van Hillegersberg, MD, PhD The Annals of Thoracic Surgery Volume 102, Issue 6, Pages 1798-1804 (December 2016) DOI: 10.1016/j.athoracsur.2016.08.027 Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Box plots showing (A) the distribution of gastric fundus dose variables (mean dose [Dmean], minimum dose [Dmin], dose that covered at least 50% of the volume [D50], maximum dose [Dmax]), and (B) the distribution of gastric fundus volume percentages receiving a minimum amount of Gy (percentage of the volume that received at least 25, 30, and 35 Gy [V20, V25, V30, V35, respectively]) between patients with and without anastomotic leakage. *Variables significantly associated with anastomotic leakage. The Annals of Thoracic Surgery 2016 102, 1798-1804DOI: (10.1016/j.athoracsur.2016.08.027) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Examples of treatment planning computed tomographic (CT) scans with dose distributions in (A) a patient who experienced postoperative anastomotic leakage after receiving a mean dose to the gastric fundus of 41.2 Gy and (B) a patient who did not experience postoperative anastomotic leakage after receiving a mean dose to the gastric fundus of 11.8 Gy. The areas within the yellow, light blue, dark blue, and purple lines received at least 40, 30, 20, and 10 Gy, respectively. The Annals of Thoracic Surgery 2016 102, 1798-1804DOI: (10.1016/j.athoracsur.2016.08.027) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions