Richard T. Scott, M.D., Daniela Galliano, M.D. Fertility and Sterility

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The challenge of embryonic mosaicism in preimplantation genetic screening Richard T. Scott, M.D., Daniela Galliano, M.D. Fertility and Sterility Volume 105, Issue 5, Pages 1150-1152 (May 2016) DOI: 10.1016/j.fertnstert.2016.01.007 Copyright © 2016 Terms and Conditions

Figure 1 Illustration of the change in interpretation of aCGH results with contemporary PGS screening versus those defining a new midrange designation for biopsies that may contain mosaicism. Note that the actual analysis of the trophectoderm would remain unchanged. The traditional interpretation seeks only to separate disomy from trisomy. The revised interpretation considers values near the prior threshold value separating disomy from trisomy to be considered mosaic. Fertility and Sterility 2016 105, 1150-1152DOI: (10.1016/j.fertnstert.2016.01.007) Copyright © 2016 Terms and Conditions