Treatment and outcomes of aortic endograft infection

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Presentation transcript:

Treatment and outcomes of aortic endograft infection Matthew R. Smeds, MD, Audra A. Duncan, MD, Michael P. Harlander-Locke, MPH, Peter F. Lawrence, MD, Sean Lyden, MD, Javariah Fatima, MD, Mark K. Eskandari, MD Sean P. Steenberge, MS, Tadaki M. Tomita, MD, Mark Morasch, MD, Jeffrey Jim, MD, Lewis C. Lyons, MD, Kristofer Charlton-Ouw, MD, Harith Mushtaq, MD, Samuel S. Leake, BS, Raghu Motaganahalli, MD, Peter Nelson, MD, Godfrey Parkerson, MD, Sherene Shalhub, MD, Paul Bove, MD, Gregory Modrall, MD, Victor Davila, MD, Samuel Money, MD, Nasim Hedayati, MD, Ahmed Abou-Zamzam, MD, Christopher Abularrage, MD, Catherine Wittgen, MD Matthew R. Smeds, MD, Audra A. Duncan, MD, Michael P. Harlander-Locke, MPH, Peter F. Lawrence, MD, Sean Lyden, MD, Javariah Fatima, MD, Mark K. Eskandari, MD Sean P. Steenberge, MS, Tadaki M. Tomita, MD, Mark Morasch, MD, Jeffrey Jim, MD, Lewis C. Lyons, MD, Kristofer Charlton-Ouw, MD, Harith Mushtaq, MD, Samuel S. Leake, BS, Raghu Motaganahalli, MD, Peter Nelson, MD, Godfrey Parkerson, MD, Sherene Shalhub, MD, Paul Bove, MD, Gregory Modrall, MD, Victor Davila, MD, Samuel Money, MD, Nasim Hedayati, MD, Ahmed Abou- Zamzam, MD, Christopher Abularrage, MD, Catherine Wittgen, MD  Journal of Vascular Surgery  Volume 63, Issue 2, Pages 332-340 (February 2016) DOI: 10.1016/j.jvs.2015.08.113 Copyright © 2016 Society for Vascular Surgery Terms and Conditions

Fig 1 Time from the initial endograft placement in endovascular aortic repair (EVAR) or thoracic endovascular aortic repair (TEVAR) to the diagnosis of aortic endograft infection in (A) patients with gram-positive and gram-negative infections and (B) those with polymicrobial, fungal, and negative culture infections. Journal of Vascular Surgery 2016 63, 332-340DOI: (10.1016/j.jvs.2015.08.113) Copyright © 2016 Society for Vascular Surgery Terms and Conditions

Fig 2 Flow chart details the management of patients with aortic endograft infection. Abx, Antibiotic; EVAR, endovascular aortic repair; NAIS, neoaortoiliac system; TEVAR, thoracic endovascular aortic repair. Journal of Vascular Surgery 2016 63, 332-340DOI: (10.1016/j.jvs.2015.08.113) Copyright © 2016 Society for Vascular Surgery Terms and Conditions

Fig 3 Patient survival (A) overall, (B) infected endovascular aortic repair (EVAR) vs thoracic endovascular aortic repair (TEVAR), (C) gram-positive infections vs gram-negative infections, (D) polymicrobial infections vs gram-positive, gram-negative, and fungal infections, (E) in-line reconstruction vs extra-anatomic bypass, and (F) autogenous reconstruction vs prosthetic grafts soaked in antibiotics (Abx, in-line and bypass) vs prosthetic grafts not soaked in antibiotics (in-line and bypass). Journal of Vascular Surgery 2016 63, 332-340DOI: (10.1016/j.jvs.2015.08.113) Copyright © 2016 Society for Vascular Surgery Terms and Conditions