Single-Nucleotide Polymorphisms and Haplotypes in the VEGF Receptor 3 Gene and the Haplotype GC in the VEGFA Gene Are Associated with Psoriasis in Koreans  Joo-Heung Lee, Eun-Young Cho, Jung-Hyun Namkung, Eugene Kim, Sook Kim, Eun-Soon Shin, Jong-Eun Lee, Jun-Mo Yang  Journal of Investigative Dermatology  Volume 128, Issue 6, Pages 1599-1603 (July 2008) DOI: 10.1038/sj.jid.5701204 Copyright © 2008 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 Map of VEGFA, VEGFC, FIGF, and FLT4 on chromosome 6p12 (21.4kb), 4q34.1–q34.3 (116.3kb), Xp22.31 (41.5kb), and 5q35.3 (53.7kb), respectively. Coding exons are marked by black blocks, and the 5′- and 3′-UTRs are marked by gray blocks. The first base of the translation start site is denoted as nucleotide +1. Genotyped polymorphisms in the four genes are marked. Minor allele frequencies of the polymorphism in the 48 samples are distinguished as over 10% or less. Dots indicate the polymorphisms genotyped in a larger population (n=717). LD among the tag SNPs and their tagged SNPs are presented in r2 and the haplotypes are listed in boxes. Journal of Investigative Dermatology 2008 128, 1599-1603DOI: (10.1038/sj.jid.5701204) Copyright © 2008 The Society for Investigative Dermatology, Inc Terms and Conditions