Aortic and innominate routes for transcatheter aortic valve implantation Jean Porterie, MD, Nicolas Mayeur, MD, PhD, Thibaut Lhermusier, MD, PhD, Nicolas.

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Aortic and innominate routes for transcatheter aortic valve implantation Jean Porterie, MD, Nicolas Mayeur, MD, PhD, Thibaut Lhermusier, MD, PhD, Nicolas Dumonteil, MD, Thomas Chollet, MD, Olivier Lairez, MD, PhD, Bertrand Marcheix, MD, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 157, Issue 4, Pages 1393-1401.e7 (April 2019) DOI: 10.1016/j.jtcvs.2018.07.098 Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Institutional TAVR volume and access route strategies. TAVI, Transcatheter aortic valve implantation; TF, transfemoral; TA, transapical; AA, ascending aorta; IA, innominate artery access; LVEF, left ventricular ejection fraction; COPD, chronic obstructive pulmonary disease; ITA, internal thoracic artery; SC, subclavian. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 1393-1401.e7DOI: (10.1016/j.jtcvs.2018.07.098) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Figure E1 NYHA functional status. Proportions of patients in each NYHA functional class based on their symptoms. Percentages expressed are related to the number of patients alive for whom status was known at each time point. NYHA, New York Heart Association. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 1393-1401.e7DOI: (10.1016/j.jtcvs.2018.07.098) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Figure E2 Valve hemodynamics during the follow-up period. Mean transvalvular gradient and indexed effective orifice area over time. Baseline versus follow-up *P < .0001. No significant changes in valve hemodynamics were observed during the follow-up period. Analyses of variance were done with Kruskal–Wallis test for patients (n = 107) in whom the data of the echocardiographic assessment at each time point were available. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 1393-1401.e7DOI: (10.1016/j.jtcvs.2018.07.098) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Figure E3 Kaplan–Meier analysis of freedom from all-cause mortality. CI, Confidence interval. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 1393-1401.e7DOI: (10.1016/j.jtcvs.2018.07.098) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Figure E4 Kaplan–Meier analysis of freedom from cardiovascular mortality. Deaths from unknown cause were assumed to be of cardiovascular cause. CI, Confidence interval. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 1393-1401.e7DOI: (10.1016/j.jtcvs.2018.07.098) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

After TAo-TAVI, 30-day mortality and stroke rates were 5. 3% and 1 After TAo-TAVI, 30-day mortality and stroke rates were 5.3% and 1.0%, respectively. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 1393-1401.e7DOI: (10.1016/j.jtcvs.2018.07.098) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Video 1 All the procedures were performed in a hybrid operating room by a multidisciplinary team composed of interventional cardiologists, cardiac surgeons, and cardiac anesthesiologists. All patients underwent a J-shaped manubriotomy down to the second right intercostal space. A safe entry site was exposed on the IA in most patients. The procedures were performed with a balloon-expandable or self-expanding prosthesis. Video available at: https://www.jtcvs.org/article/S0022-5223(18)32278-5/fulltext. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 1393-1401.e7DOI: (10.1016/j.jtcvs.2018.07.098) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions