Update on emergence of HIV-1 resistance to antiretroviral drug classes in an Italian national database: 2007–2009 S. Di Giambenedetto, M. Prosperi, I.

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Presentation transcript:

Update on emergence of HIV-1 resistance to antiretroviral drug classes in an Italian national database: 2007–2009 S. Di Giambenedetto, M. Prosperi, I. Fanti, B. Bruzzone, S. Paolucci, G. Penco, G. Meini, A. Di Biagio, E. Paolini, V. Micheli, P. Meraviglia, P. Castelli, P. Corsi, A. Gonnelli, M. Fabbiani, M. Zazzi, A. De Luca Clinical Microbiology and Infection Volume 17, Issue 9, Pages 1352-1355 (September 2011) DOI: 10.1111/j.1469-0691.2011.03563.x Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 (a) Evolution of antiretroviral drug usage in failing regimens from 2007 to 2009. (b) Evolution of the prevalence of resistance (at least one major IAS-2009 mutation) to any nucleoside reverse transcriptase inhibitor (NRTI), non-nucleoside reverse transcriptase inhibitor (NNRTI), protease inhibitor (PI) and non-B subtypes by calendar year from 2007 to 2009. n, number of cases used as denominator; TA, thymidine analogues (zidovudine/stavudine); Non-TA, (abacavir/didanosine/tenofovir); rtv, ritonavir; FI, fusion inhibitor; EI, entry inhibitor; INI, Integrose inhibitor. Clinical Microbiology and Infection 2011 17, 1352-1355DOI: (10.1111/j.1469-0691.2011.03563.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions