Ten years of progress in our understanding of uremic vascular calcification and disease: a decade summarized in 20 steps Vincent M. Brandenburg, Markus.

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Ten years of progress in our understanding of uremic vascular calcification and disease: a decade summarized in 20 steps Vincent M. Brandenburg, Markus Ketteler, Mariano Rodriguez Kidney International Supplements Volume 1, Issue 4, Pages 116-121 (September 2011) DOI: 10.1038/kisup.2011.27 Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 1 Distal peripheral artery with linear tram track calcification on plane X-ray (69-year-old diabetic end-stage renal disease patient). Kidney International Supplements 2011 1, 116-121DOI: (10.1038/kisup.2011.27) Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 2 Multislice computed tomography with aortic valve calcification in a 71-year-old dialysis patient. LA, left atrium; LV, left ventricle; RA, right atrium; RV, right ventricle. Kidney International Supplements 2011 1, 116-121DOI: (10.1038/kisup.2011.27) Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 3 Ulcerative calciphylaxis (61-year-old female end-stage renal disease patient). Kidney International Supplements 2011 1, 116-121DOI: (10.1038/kisup.2011.27) Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 4 Time line for a decade with landmark publications about bone and vascular disease in patients with CKD. CAC, coronary artery calcification; CKD, chronic kidney disease; ESRD, end-stage renal disease; FGF, fibroblast growth factor; KDIGO, Kidney Disease: Improving Global Outcomes; K/DOQI, Kidney Disease Outcomes Quality Initiative; PTH, parathyroid hormone; TTG, Treat-to-Goal; VDR, vitamin D receptor; VSMC, vascular smooth muscle cell. Kidney International Supplements 2011 1, 116-121DOI: (10.1038/kisup.2011.27) Copyright © 2011 International Society of Nephrology Terms and Conditions